The Neoplasia as embryological phenomenon and its implication in the animal evolution and the origin of cancer. I. A presentation of the neoplastic process and its connection with cell fusion and germline formation [PDF]
The decisive role of Embryology in understanding the evolution of animal forms is founded and deeply rooted in the history of science. It is recognized that the emergence of multicellularity would not have been possible without the formation of the first embryo.
arxiv +1 more source
A Bayesian accelerated failure time model for interval censored three-state screening outcomes [PDF]
Women infected by the Human papilloma virus are at an increased risk to develop cervical intraepithalial neoplasia lesions (CIN). CIN are classified into three grades of increasing severity (CIN-1, CIN-2, and CIN-3) and can eventually develop into cervical cancer.
arxiv +1 more source
A mutual information-based in vivo monitoring of adaptive response to targeted therapies in melanoma [PDF]
The mechanisms of adaptive resistance to genetic-based targeted therapies of solid malignancies have been the subject of intense research. These studies hold great promise for finding co-targetable hub/pathways which in turn would control the downstream non-genetic mechanisms of adaptive resistance.
arxiv +1 more source
The Neoplasia as embryological phenomenon and its implication in the animal evolution and the origin of cancer. III. The role of flagellated cell fusion in the formation of the first animal and evolutionary clues to the Warburg effect [PDF]
Cytasters have been underestimated in terms of their potential relevance to embryonic development and evolution. From the perspective discussed herein, structures such as the multiciliated cells of comb rows and balancers supporting mineralized statoliths and macrocilia in Beroe ovata point to a past event of multiflagellate fusion in the origin of ...
arxiv
Introdução: A incidência de neoplasias que acometem o Sistema Nervoso Central (SNC) tem aumentado gradativamente no mundo. No Brasil, as neoplasias encefálicas primárias são classificadas como a sétima causa de morte entre as neoplasias malignas.
Joziane de Oliveira+2 more
doaj
Objetivo: analisar as expectativas de pacientes internados devido ao diagnóstico de câncer sobre o término do tratamento e a sobrevivência à doença.
Kelly de Miranda Gonzaga Pacheco+5 more
doaj +1 more source
The Neoplasia as embryological phenomenon and its implication in the animal evolution and the origin of cancer. II. The neoplastic process as an evolutionary engine [PDF]
In this article, I put forward the idea that the neoplastic process (NP) has deep evolutionary roots and make specific predictions about the connection between cancer and the formation of the first embryo, which allowed for the evolutionary radiation of metazoans.
arxiv
Biological Effects of Stellar Collapse Neutrinos [PDF]
Massive stars in their final stages of collapse radiate most of their binding energy in the form of MeV neutrinos. The recoil atoms that they produce in elastic scattering off nuclei in organic tissue create radiation damage which is highly effective in the production of irreparable DNA harm, leading to cellular mutation, neoplasia and oncogenesis ...
arxiv +1 more source
Objetivo: analisar as reações adversas nos pacientes oncológicos em uso de inibidores de checkpoint e sua prevalência. Método: revisão integrativa da literatura, utilizando a combinação de descritores “Imunoterapia” AND “Reação adversa” AND “Neoplasias”,
Isabelle Cristine Tavares Silva Fialho+4 more
doaj +1 more source
Intrapapillary Capillary Loop Classification in Magnification Endoscopy: Open Dataset and Baseline Methodology [PDF]
Purpose. Early squamous cell neoplasia (ESCN) in the oesophagus is a highly treatable condition. Lesions confined to the mucosal layer can be curatively treated endoscopically. We build a computer-assisted detection (CADe) system that can classify still images or video frames as normal or abnormal with high diagnostic accuracy. Methods.
arxiv +1 more source