Results 51 to 60 of about 284,529 (384)

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Caracterización epidemiológica de pacientes fumadores invertidos en Cartagena, Colombia

Acta Odontológica Colombiana, 2019
Objetivo: el presente estudio se propone describir las características epidemiológicas de pacientes fumadores invertidos que asisten a consulta en la Facultad de Odontología de la Universidad de Cartagena.
Martha Carmona Lorduy, Luisa Pimienta Vásquez, Iván Porto Puerta, Margarita Pérez Martínez   +3 more
doaj   +1 more source

Afrontamiento y adaptación del adulto con cáncer: el arte del cuidado de enfermería

Aquichan, 2022
Objetivo: determinar la capacidad de afrontamiento y adaptación en personas con cáncer en tratamiento. Metodología: estudio cuantitativo y descriptivo de corte transversal; la muestra fue conformada por 100 pacientes con diagnóstico de cáncer que ...
Lina Marcela Cepeda-Trujillo, Jesús Miguel Mosquera-Aguirre, Daniela Yurani Rojas-Atehortua, Alix Yaneth Perdomo-Romero   +3 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Neoplasias mamárias em canídeos [PDF]

, 2009
As neoplasias em pequenos animais têm grande relevância na clínica de animais de companhia, não só pela sua incidência crescente, como pela sua gravidade.
Esteves, Fernando, Lemos, Maria, Paiva, Rita, Santos, Carla, Vala, Helena   +4 more
core  

Cowden syndrome - Diagnostic skin signs [PDF]

, 2001
Cowden syndrome is a rare autosomal dominant familial cancer syndrome with a high risk of breast cancer. The most important clinical features include carcinomas of the breast and thyroid, and hamartomatous polyps of the gastrointestinal tract.
Burgdorf, Walter H. C., Hildenbrand, C., Lautenschlager, Stephan   +2 more
core   +1 more source

Cytokine, Chemokine, and Neurofilament Light Chain Signatures in LGI1 Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the value of cytokine, chemokine, and neurofilament light chain (NfL) concentrations in predicting relapse risk, chronic epilepsy, and functional impairment in LGI1 autoimmune encephalitis (AE). Methods Cytokines/chemokines (IL‐1‐beta, IL‐2, IL‐4, IL‐5, IL‐6, IL‐8/CXCL8, IL‐10, IL‐12p70, IL‐13, IL‐17A, GM‐CSF, TNF ...
Albert Aboseif, Georgios Mangioris, Binxia Yang, Vanessa K. Pazdernik, Jeffrey W. Britton, Divyanshu Dubey, Eoin P. Flanagan, Sarosh R. Irani, Gregory S. Day, Charles L. Howe, A. Sebastian López‐Chiriboga, Andrew McKeon, John R. Mills, Yahel Segal, Michel Toledano, Ivana Vodopivec, Sean J. Pittock, Anastasia Zekeridou   +17 more
wiley   +1 more source

Mapping of the main types of neoplasms among children and adolescents across the regional health agencies from the Rio de janeiro state, Brazil / Mapeamento das principais neoplasias infanto-juvenis nas regionais de saúde do Rio de Janeiro

Revista de Pesquisa Cuidado é Fundamental Online, 2020
Objetivo: Analisar os principais tipos de neoplasia malignas em pacientes de 0 a 19 anos de idade nas regionais de saúde do estado do Rio de Janeiro.
Rayssa Goulart Valente, Aline Cerqueira Santos Santana da Silva, Virginia Maria de Azevedo Oliveira Knupp, Bianka Queiroz da Silva, Leila Leontina do Couto Barcia, José Antônio de Sá Neto   +5 more
doaj   +1 more source

HIV Infection and Non-AIDS-Defining Malignancies: an Outpatient Clinic Experience [PDF]

, 2014
Introdução: Os doentes infectados pelo Vírus da Imunodeficiência Humana têm um risco elevado de desenvolver diferentes tipos de Neoplasias. Com a introdução da terapêutica anti-retroviral de alta potência, e consequente aumento da sobrevida, assistimos ...
Fevereiro, MC
core  

Embolization in an adrenocortical carcinoma as palliative therapy [PDF]

, 1999
Background: With an annual incidence of 0.2% of new cases per 100,000 inhabitants, adrenocortical carcinoma is rare. In advanced tumor only palliative treatment modalities are practicable. Because of scarcity of the tumor, standard treatment has not been
Braunschweig, R., Forstpointner, Roswitha, Kühl, M., Lang, N., Meissner, H., Schalhorn, Andreas   +5 more
core   +1 more source