Results 81 to 90 of about 284,529 (384)

Putting the brakes on mammary tumorigenesis: Loss of STAT1 predisposes to intraepithelial neoplasias

open access: yesOncoTarget, 2011
Multiparous Stat1−/− mice spontaneously develop mammary tumors with increased incidence: at an average age of 12 months, 55% of the animals suffer from mammary cancer, although the histopathology is heterogeneous.
Christine Schneckenleithner   +11 more
semanticscholar   +1 more source

Engineering Bacteria as Living Therapeutics in Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen   +6 more
wiley   +1 more source

Neoplasia

open access: yes, 2023
Due to our environmental change, neoplasia is much more common worldwide. And nowadays some well-developed modalities of cancer diagnosis are available. That is why we have to learn about neoplasia. Neoplasia is defined as a genetic disorientation of cell growth that is triggered by acquired or less commonly inherited mutations affecting a single cell ...
openaire   +2 more sources

SP1‐Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Laser capture microdissection‐based proteomics of pancreatic intraepithelial neoplasia (PanIN) identifies specificity protein 1 (SP1) as a key driver of tumorigenesis and progression in pancreatic cancer through glycolytic remodeling. SP1 enhances aerobic glycolysis by transcriptionally activating 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase ...
Hexing Hang   +21 more
wiley   +1 more source

Salivary gland neoplasms: a study of 119 cases [PDF]

open access: yes, 2003
BACKGROUND: The purpose of this study was to review clinicopathological aspects of salivary glands tumours from 1980 through 1997 at Departament of Pathology of Paulista School of Medicine - Federal University of São Paulo - UNIFESP.
Abrahão, Márcio   +5 more
core   +3 more sources

Birt-Hogg-Dubé renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expression

open access: yesBMC Medical Genomics, 2010
BackgroundGermline mutations in the folliculin (FLCN) gene are associated with the development of Birt-Hogg-Dubé syndrome (BHDS), a disease characterized by papular skin lesions, a high occurrence of spontaneous pneumothorax, and the development of renal
J. Klomp   +20 more
semanticscholar   +1 more source

Caracterização clínica, diagnóstico histopatológico e distribuição geográfica das neoplasias mamárias em cadelas de Salvador, Bahia

open access: yes, 2012
Os tumores espontâneos da glândula mamaria representam, nas cadelas, a neoplasia mais observada na clinica de pequenos animais, justificando o grande interesse dos pesquisadores no estudo dessa lesao.
J. M. D. M. L. Toríbio   +8 more
semanticscholar   +1 more source

Osteosarcoma in the Skull of a Holstein Heifer [PDF]

open access: yes, 2015
A-2-years-old heifer showed a mass on the frontal part of the skull. Cytological analysis displayed pleomorphic, polyedric and fusiform cells with extracellular hyaline material.
Gimeno, Eduardo Juan   +2 more
core   +1 more source

Case Series of Nizon‐Isidor Syndrome by Heterozygous Variants in MED12L With Further Evidence of Mitotic Instability in One Case With Diploid–Triploid Mosaicism

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nizon‐Isidor syndrome is a rare disorder caused by heterozygous variants in MED12L, with only eight documented cases in the literature. Here, we present three additional cases of this syndrome. Proband 1 was a 7‐year‐old female who presented with developmental delay, right‐leg hemihypertrophy, laryngeal cleft, esotropia, abnormal skin ...
Russell Stewart   +336 more
wiley   +1 more source

Neoplasias mamárias em canídeos

open access: yesMillenium, 2016
As neoplasias em pequenos animais têm grande relevância na clínica de animais de companhia, não só pela sua incidência crescente, como pela sua gravidade.
Maria Madalena Lemos   +4 more
doaj  

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