Results 31 to 40 of about 1,080 (164)

Radioterapia intraoperatória como protocolo de tratamento do câncer de mama inicial

Einstein (São Paulo)
OBJETIVO: Avaliar a experiência inicial de implementação e aplicação de radioterapia única e intraoperatória com feixe de elétrons em pacientes selecionadas com diagnóstico de câncer de mama em estágio inicial.
Silvio Eduardo Bromberg, Rodrigo de Morais Hanriot, Afonso Celso Pinto Nazário   +2 more
doaj   +1 more source

State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge

MedComm, Volume 7, Issue 2, February 2026.
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding, Zai Luo, Liao Zhang, Shaopeng Zhang, Renchao Zhang, Zhengjun Qiu, Chen Huang   +6 more
wiley   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Grau de subestimação histopatológica por core biopsy de lesões não palpáveis da mama Underestimation of malignancy of core needle biopsy for nonpalpable breast lesions

Revista Brasileira de Ginecologia e Obstetrícia, 2011
OBJETIVO: Determinar o grau de subestimação de core biopsy, guiada por imagem, de lesões impalpáveis da mama subsequentemente submetidas à exérese cirúrgica.
Aline Valadão Britto Gonçalves, Luiz Claudio Santos Thuler, Fabíola Procaci Kestelman, Pedro Aurélio Ormonde do Carmo, Carlos Frederico de Freitas Lima, Rosana Cipolotti   +5 more
doaj   +1 more source

Histopathologic Findings in Three Dogs With Metastatic Carcinoma Presenting With Bronchovascular Bundle Thickening on Computed Tomography

Veterinary Radiology &Ultrasound, Volume 67, Issue 1, January 2026.
ABSTRACT Carcinoma metastasis to the lungs can occur via multiple pathways, most notably via hematogenous, lymphangitic, or aerogenous routes. Computed tomographic (CT) characteristics of these metastatic pathways can vary, with only sparse reports of bronchovascular bundle thickening (BVBT) associated with metastatic carcinoma.
Robert Wise, Maria Mulvihill, Jennifer Reetz, Bianca Pfisterer, Wilfried Mai   +4 more
wiley   +1 more source

Primary Hepatic Hemangiosarcoma With Hemoperitoneum in a Dog: Clinical Course and Therapeutic Outcome

Case Reports in Veterinary Medicine, Volume 2026, Issue 1, 2026.
A 14‐year‐old neutered male mixed‐breed dog presented with hemoperitoneum secondary to rupture of a primary hepatic mass. Following stabilization with whole blood transfusion, a hepatic lobectomy was performed. Histopathological examination and CD31 immunolabeling confirmed a diagnosis of hemangiosarcoma.
Myeong-Yeon Lee, Jong-Hyun Moon, Jinsu Mok, Dowoo Lim, Ju-Yeong Kim, Seo-Yeong Jung, Eunbin Jeong, Hyomi Jang, Dong-In Jung, Iosif Vasiu   +9 more
wiley   +1 more source

From Gene to Enzyme: Multidimensional Decoding of the GGT Molecular Family and Its Clinical Tumor Diagnosis

Cancer Medicine, Volume 14, Issue 23, December 2025.
ABSTRACT Background Gamma‐glutamyltransferase (GGT) is a membrane‐bound enzyme involved in glutathione metabolism and oxidative stress regulation. Although it is traditionally viewed as a liver function marker, emerging evidence suggests that its aberrant expression is closely associated with tumorigenesis, progression, and therapeutic resistance ...
Fei Wang, Jianshan Yang, Feng Zhu, Xuebing Xu, Junpeng Zhao, Xudong Xie, Xuyang He, Yuxuan Huang, Lirong Zhou, Xiaogang Hu, Xiaomin Lu, Mingbing Xiao   +11 more
wiley   +1 more source

DIAGNÓSTICO DE CÂNCER DE MAMA: SENTIMENTOS, COMPORTAMENTOS E EXPECTATIVAS DE MULHERES

Revista Eletrônica de Enfermagem, 2006
RESUMO: O câncer de mama é a neoplasia maligna responsável pelo maior número de óbitos em mulheres no mundo, inclusive no Brasil. Considerando que a mulher vivencia situações singulares, após a descoberta da doença, que interessam à assistência de saúde.
Malena de Fátima Silva Regis, Sonia Mara Faria Simões   +1 more
doaj   +1 more source

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Reinventando a vida: proposta para uma abordagem sócio-antropológica do câncer de mama feminina

Cadernos de Saúde Pública, 2002
O artigo objetiva analisar as representações sociais do câncer de mama e, com base nessa análise, discutir a possibilidade da inclusão de aspectos simbólicos na abordagem dessa doença.
Gomes Romeu, Skaba Márcia Marília Vargas Fróes, Vieira Roberto José da Silva   +2 more
doaj