Results 31 to 40 of about 20,119 (233)

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Anticancer Molecular Mechanisms of Curcuminoids: An Updated Review of Clinical Trials

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Curcuminoids remain one of the most studied dietary polyphenols as a cancer prevention and treatment agent. Inflammation and tumor progression are related to the NF‐κB signaling pathway, which is also suppressed by curcuminoids. Curcuminoids prevent the activation of a variety of signaling pathways, including the MAPK, PI3K/Akt, and NF‐kB pathways ...
Ushna Momal, Muhammad Shahbaz, Asfa Perween, Muhammad Hammad ul Hassan, Hammad Naeem, Zubda Shahid, Muzzamal Hussain, Muhammad Imran, Suliman A. Alsagaby, Waleed Al Abdulmonem, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Tadesse FentaYehuala, Samy Selim, Ehab M. Mostafa   +14 more
wiley   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Histopathologic Findings in Three Dogs With Metastatic Carcinoma Presenting With Bronchovascular Bundle Thickening on Computed Tomography

Veterinary Radiology &Ultrasound, Volume 67, Issue 1, January 2026.
ABSTRACT Carcinoma metastasis to the lungs can occur via multiple pathways, most notably via hematogenous, lymphangitic, or aerogenous routes. Computed tomographic (CT) characteristics of these metastatic pathways can vary, with only sparse reports of bronchovascular bundle thickening (BVBT) associated with metastatic carcinoma.
Robert Wise, Maria Mulvihill, Jennifer Reetz, Bianca Pfisterer, Wilfried Mai   +4 more
wiley   +1 more source

Grau de subestimação histopatológica por core biopsy de lesões não palpáveis da mama Underestimation of malignancy of core needle biopsy for nonpalpable breast lesions

Revista Brasileira de Ginecologia e Obstetrícia, 2011
OBJETIVO: Determinar o grau de subestimação de core biopsy, guiada por imagem, de lesões impalpáveis da mama subsequentemente submetidas à exérese cirúrgica.
Aline Valadão Britto Gonçalves, Luiz Claudio Santos Thuler, Fabíola Procaci Kestelman, Pedro Aurélio Ormonde do Carmo, Carlos Frederico de Freitas Lima, Rosana Cipolotti   +5 more
doaj   +1 more source

Myelodysplastic syndrome secondary to chemo: and radiotherapy MDS related to the treatment [PDF]

, 2006
The leukaemogenic effect of chemotherapeutic agents after treatment for other malignancies have been well described. Myelodysplastic syndrome secondary to chemo- and radiotherapy (MDS-t) usually develops four to seven years after the initial exposure to ...
Chauffaille, Maria de Lourdes Lopes Ferrari, Pinheiro, Ronald F.   +1 more
core   +3 more sources

Primary Hepatic Hemangiosarcoma With Hemoperitoneum in a Dog: Clinical Course and Therapeutic Outcome

Case Reports in Veterinary Medicine, Volume 2026, Issue 1, 2026.
A 14‐year‐old neutered male mixed‐breed dog presented with hemoperitoneum secondary to rupture of a primary hepatic mass. Following stabilization with whole blood transfusion, a hepatic lobectomy was performed. Histopathological examination and CD31 immunolabeling confirmed a diagnosis of hemangiosarcoma.
Myeong-Yeon Lee, Jong-Hyun Moon, Jinsu Mok, Dowoo Lim, Ju-Yeong Kim, Seo-Yeong Jung, Eunbin Jeong, Hyomi Jang, Dong-In Jung, Iosif Vasiu   +9 more
wiley   +1 more source

Prevalência de sintomas depressivos e ansiosos em pacientes com câncer internados no Hospital Universitário-UFSC [PDF]

, 2004
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Buratti, Sheila Fantin
core  

The role of endothelial cells in hematologic malignancies [PDF]

, 2008
A neoformação vascular constitui evento essencial para que ocorra o desenvolvimento humano. Nesta fase, o sistema vascular sofre expansão. Células endoteliais maduras (ECs) irão compor a parede dos vasos, enquanto células endoteliais oriundas da medula ...
CHAMONE, Dalton A. F., GODOY, Carla R. T., PEDROSO-MEIRELES, Ana Luísa L., PEREIRA, Juliana   +3 more
core   +2 more sources

From Gene to Enzyme: Multidimensional Decoding of the GGT Molecular Family and Its Clinical Tumor Diagnosis

Cancer Medicine, Volume 14, Issue 23, December 2025.
ABSTRACT Background Gamma‐glutamyltransferase (GGT) is a membrane‐bound enzyme involved in glutathione metabolism and oxidative stress regulation. Although it is traditionally viewed as a liver function marker, emerging evidence suggests that its aberrant expression is closely associated with tumorigenesis, progression, and therapeutic resistance ...
Fei Wang, Jianshan Yang, Feng Zhu, Xuebing Xu, Junpeng Zhao, Xudong Xie, Xuyang He, Yuxuan Huang, Lirong Zhou, Xiaogang Hu, Xiaomin Lu, Mingbing Xiao   +11 more
wiley   +1 more source