Results 1 to 10 of about 64,287,349 (187)

Transcriptomic Profiling of Canine Mammary Tumours Reveals Significant Heterogeneity Between and Within Histological Classes

Veterinary and Comparative Oncology, Volume 24, Issue 3, Page 444-457, September 2026.
ABSTRACT This study presents a comprehensive transcriptomic analysis of 128 canine mammary tumours (CMTs), aiming to characterize their molecular landscape. Differential gene expression analysis (DGE), gene set enrichment analysis (GSEA) and clustering based on the human PAM50 gene panel were applied to explore molecular differences between the ...
Ingrid Marie Moberg, Nina Hansen, Helga Bergholtz, Kaja Sverdrup Borge, Gjermund Gunnes, Ellen Frøysadal Arnet, Ole Albert Guttersrud, Monica Hongrø Solbakken, Frode Lingaas   +8 more
wiley   +1 more source

Análisis de la amplificación del gen C-MYC por medio de la Hibridación in situ Fluorescencia (FISH) en pacientes con cáncer de mama.

Iatreia, 2010
El proto-oncogen C- MYC se relaciona con diversos tipos de neoplasias en humanos; participa en la regulación del ciclo celular, apoptosis, proliferación y diferenciación celular.
Mariano Ospina, Elvia I. Góez, Enoc Ahumada Enoc Ahumada, Hamilton Ceballos Hamilton Ceballos, Carlos Mario Muneton Carlos Mario Muneton   +4 more
doaj  

Importancia de la pesquisa del cáncer de mama

Revista Finlay, 2017
El cáncer, es uno de los mayores problemas de Salud Pública en el mundo, siendo en términos epidemiológicos, la neoplasia maligna que más se diagnostica y la mayor causa de muerte en el sexo femenino.
Dinorah García Roque, Yaiset Borges de la Oliva   +1 more
doaj   +2 more sources

Transcriptomic and microRNA Profiling Suggest a Candidate RIPPLY1–cfa‐miR‐187 Relationship in Canine Mammary Gland Tumours From Dogs With Confirmed Metastasis

Veterinary and Comparative Oncology, Volume 24, Issue 3, Page 631-642, September 2026.
ABSTRACT Canine mammary gland tumours (MGT) represent a common malignancy in intact female dogs, with a high metastasis rate approaching 50% and a poor prognosis. However, metastasis‐related genes remain largely unelucidated. Accordingly, we aimed to identify differentially expressed mRNAs and miRNAs in primary canine MGT tissues from dogs with or ...
Shaohsu Wang, Masashi Takahashi, Hui‐Wen Chen, Nobuhiro Nozaki, Mohammad Arif, Yutaro Ide, Yoshiyuki Akiyama, Sirazul Islam, Tatsuro Hifumi, Shinji Hirano, Noriaki Miyoshi, Osamu Yamato, Daiki Kato, Takayuki Nakagawa, Naoki Miura   +14 more
wiley   +1 more source

Assessment of the contents related to screening on Portuguese language websites providing information on breast and prostate cancer

Cadernos de Saúde Pública, 2013
The objective of this study was to assess the quality of the contents related to screening in a sample of websites providing information on breast and prostate cancer in the Portuguese language. The first 200 results of each cancer-specific Google search
Daniel Ferreira, Helena Carreira, Susana Silva, Nuno Lunet   +3 more
doaj   +1 more source

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

LÍPIDOS DE LA DIETA Y CÁNCER DE MAMA

Medicentro, 2011
A nivel mundial, el cáncer de mama es el más común entre las mujeres y es el responsable de aproximadamente uno de los 10 millones de neoplasias diagnosticadas cada año en ambos sexos.
Otmara Guirado Blanco, Eduard Escrich Escriche   +1 more
doaj  

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Conocimientos de los factores de riesgo asociados al cáncer de mama. Sancti Spíritus 2008.

Gaceta Médica Espirituana, 2012
Introducción. El cáncer de mama es una de las neoplasias malignas más frecuentes en Cuba y en el mundo, y sobre todo en nuestro policlínico. Objetivo: Identificar el conocimiento de los principales factores de riesgo asociado al cáncer de mama y el auto
Lourdes María Rodríguez Castro, Yara Lidia Morgado Bode, Nelson Morejón Morejón, Yunis González Herrera   +3 more
doaj  

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source