Results 181 to 190 of about 1,272,565 (330)

The roles and applications of extracellular vesicles in cancer

Molecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Irreversible electroporation synergizes with oncolytic virus enhances the infiltration of cytotoxic T lymphocytes in the tumor immune microenvironment: a leap from focal therapy to immunotherapy for prostate cancer. [PDF]

J Immunother Cancer
Xia ZY, Xiang JC, Xu JZ, Sun JX, Wang S, Xia QD.   +5 more
europepmc   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Trichilemmal Carcinoma in a Patient With Oculocutaneous Albinism. [PDF]

Cureus
Theriot T, Joseph JM, Falgout L, Haas C.
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Blastic plasmacytoid dendritic cell neoplasm: is it time to redefine the standard of care?

Expert Review of Hematology, 2012
P. Piccaluga, S. Paolini, M. Sapienza, S. Pileri   +3 more
semanticscholar   +1 more source

Real-life sensitivity of flow cytometry minimal residual disease assessment for plasma cell neoplasms

Blood Cancer Journal
Dragan Jevremovic, Min Shi, Pedro Horna, Gregory E. Otteson, Michael M. Timm, Linda B. Baughn, Patricia T. Greipp, Wilson I. Gonsalves, Prashant Kapoor, Morie A. Gertz, Moritz Binder, Francis K. Buadi, Jiehao Zhou, Angela Dispenzieri, Taxiarchis Kourelis, Eli Muchtar, S. Vincent Rajkumar, Shaji K. Kumar, Horatiu Olteanu   +18 more
openaire   +3 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Gigantic, Sixteen-Pound Carcinoma Ex Pleomorphic Adenoma of the Neck. [PDF]

Clin Case Rep
Rothka AJ, Ferraro M, Bavier R, Saltagi M, Bhele S, Goyal N, Slonimsky G.   +6 more
europepmc   +1 more source

Rapid postoperative recurrence of a cranial multilobular tumor of bone in a young dog [PDF]

, 2017
Banks, Dernell, Diamond, Fukui, Hay, Karin, Kim, Liptak, Loukopoulos, Morrison, Straw, Thompson, Vancil, Webb   +13 more
core   +1 more source