Results 101 to 110 of about 508,628 (245)
Two Unusual Small Intestinal Neoplasms, both with Anaemia [PDF]
Jim Richardson
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ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee+9 more
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Causal links between iron status, mitochondrial function, and laryngeal and hypopharyngeal cancers: a Mendelian study. [PDF]
Zhao J+6 more
europepmc +1 more source
Post-mortem Findings of Case of? Neoplasm of Lung, shown at the Meeting of the Section on December 10, 1920. [PDF]
Maurice Cassidy
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Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan+4 more
wiley +1 more source
Isolated Mu Heavy Chain Deposition Disease-A Rare Cause of Spontaneous Splenic Rupture in a Young Adult. [PDF]
Hlaing SS+4 more
europepmc +1 more source
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella+18 more
wiley +1 more source