Results 131 to 140 of about 1,272,281 (247)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Machine learning-based models for tumor mutation burden prediction in gastrointestinal cancers: a systematic review and meta-analysis. [PDF]

Discov Oncol
Rahimi P, Atighi F, Rezaei B, Rezaee H, Abdelbaset M, Nazari F, Zarrehparvar Ghouchani Nezhad S, Moradi Kashkoli M, Ghaffarzadeh A, Taghavi F, Goudarzi P, Samavarchitehrani A, Marashi A, Esmaeili Y, Zhian Zargaran F, Shirdel A, Asadi Anar M, Mousavi S.   +17 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Primary carcinoma of the rete testis in a Nellore bull. [PDF]

Vet Res Commun
da Silva NV, Santos RL, de Carvalho TF, de Paula NF, Pereira MF, Micai RA, Pereira GF, Delfiol DJZ, Horr M, Toma HS, Nogueira GM.   +10 more
europepmc   +1 more source

THYMIC NEOPLASMS

Journal of Thoracic Surgery, 1956
D B, EFFLER, L J, MCCORMACK
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreatic Head With Atypical Presentation in a Young Woman: A Case Report. [PDF]

Cureus
Abarca Ruiz JW, Borja Velasco CA, Suárez Caicedo MN, Arteaga Morocho EA, Redroban Tufino EJ, Valdivieso Maggi JA, Corella Sanguil PC, Viteri Paredes IP, Barrera Idrovo LA, Salazar Quevedo LG.   +9 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Outcomes of Mohs Micrographic Surgery Compared to Wide Local Excision for Malignant Melanoma and Melanoma In Situ. [PDF]

Cureus
Goldstein DR, Koch RS, Emam R, Nguyen KT, Raman J, Pirtle FA, Goldstein LD, Tarbox M, Verma KK, Posligua A.   +9 more
europepmc   +1 more source