Results 111 to 120 of about 601,571 (336)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Endoscopic surgery of the paranasal sinuses and skull base neoplasms with the use of the computerassisted navigation system (CANS) in pediatric practice

Alʹmanah Kliničeskoj Mediciny, 2016
Background: In the last 10 years, the use of computer-assisted navigation systems (CANS) in endo-nasal endoscopic surgery of the paranasal sinuses and skull base in adults has been well studied.
I. N. Vorozhtsov, N. S. Grachev, A. N. Nasedkin   +2 more
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

The use of nanoparticles in diagnosis and treatment of breast cancer: A review

پژوهان, 2015
Introduction: Nowadays, cancer is one of the most important health concerns in modern societies. The application of nanoparticles has resulted in new possibilities for the diagnosis, tumor imaging and treatment of human cancers.
Maryam Salehzadeh, Parham Norouzian, Roghayeh Abbasalipourkabir   +2 more
doaj  

Olfactory Neuroblastoma: Diagnostic Difficulty [PDF]

, 2011
Olfactory neuroblastoma is an uncommon malignant tumor of sinonasal tract arising from the olfactory neuro epithelium. The olfactory neuroblastomas presenting with divergent histomorphologies like, epithelial appearance of cells, lacking a neuro ...
Biswas, Siddhartha, MN, Vidya, S, Vijay Shankar, Shivakumar, Swarna   +3 more
core   +1 more source

THE OCCURRENCE OF MALIGNANT NEOPLASMS IN THE YOUNG [PDF]

, 1915
A. S. Warthin
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Hexavalent chromium in fish from the Sepetiba Bay in Rio de Janeiro, Brazil: a risk assessment to human health

Revista Ambiente & Água, 2011
Introduction: Certain metals, among them hexavalent chromium influence the stability of ecosystems and cause adverse effects on human health. Thus, this study aimed to estimate a risk model of human health associated with fish consumption from the ...
Carla da Costa Cruz, Carlos Alexandre Rey Matias, Anne Karin Madureira da Mota, Aldo Pacheco Ferreira, Adalberto Luiz Miranda Filho   +4 more
doaj   +1 more source

THE INITIAL SEATS OF NEOPLASMS AND THEIR RELATIVE FREQUENCY [PDF]

, 1891
W. ROGER WILLIAMS
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source