Results 121 to 130 of about 1,663,966 (386)
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo+8 more
wiley +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Erythrocyte Glycolysis in Patients with Malignant Neoplasms and Other Chronic Diseases [PDF]
John E. Ultmann+3 more
openalex +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Unique Finding of a Fetal Rhabdomyoma in the Lacrimal Gland
Fetal rhabdomyomas are a rare neoplasm composed of immature striated muscle cells that resemble rhabdomesenchymal cells during weeks 6-10 of embryogenesis.
Alyssa Erin Sidoff+3 more
doaj +1 more source
Feline vestibular disorders. Part II: diagnostic approach and differential diagnosis. [PDF]
Results of a neurological examination usually permit localisation of a vestibular disorder to either the central or peripheral parts of the vestibular system. Many different disorders located in the same part of the vestibular system will produce similar
LeCouteur, RA, Vernau, KM
core
Pathological features and diagnosis of intraductal papillary mucinous neoplasm of the pancreas.
Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a noninvasive epithelial neoplasm of mucin-producing cells arising in the main duct (MD) and/or branch ducts (BD) of the pancreas.
V. Castellano-Megías+3 more
semanticscholar +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
THE BEHAVIOR IN TRANSPLANT OF LYMPHOCYTIC NEOPLASMS ARISING FROM PARENTAL THYMIC GRAFTS IN IRRADIATED, THYMECTOMIZED HYBRID MICE [PDF]
L. W. Law, M Potter
openalex +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source