Results 151 to 160 of about 1,663,966 (386)
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Studies in the Genetics of Human Neoplasms: Cancer of the Breast, Based upon 201 Family Histories
, 1937 R. P. Martynova
openalex +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Revisiting the mortality of France and Italy with the multiple-cause-of-death approach [PDF]
In this paper, we use the multiple cause-of-death approach to compare the mortality profiles of France and Italy in 2003. Our analysis leads to a substantial re-evaluation of the role played by certain conditions in the process leading to death ...
Aline Desesquelles +6 more
core
A NEOPLASM OF MONOCYTES OF MICE AND ITS RELATION TO SIMILAR NEOPLASMS OF MAN [PDF]
, 1939 J. Fürth
openalex +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
International Medical Case Reports Journal, 2019 Mehdi Salehipour,1 Niloofar Dastgheib,2 Masood Hosseinzadeh,3 Alireza Makarem,1 Alireza Rezvani,4 Alireza Sanati,1 Sona Tayebi11Department of Urology, Shiraz University of Medical Sciences, Shiraz, Iran; 2Student Research Committee, Shiraz University of ...
Salehipour M +6 more
doaj
NEOPLASMS OF THE BLOOD-LYMPH-VASCULAR SYSTEM WITH SPECIAL REFERENCE TO ENDOTHELIOMAS
, 1925 D. Schuyler Pulford
openalex +2 more sources