Results 251 to 260 of about 704,490 (345)

Trends in tobacco smoking and bladder and lung-bronchial cancer rates among non-hispanic white Americans (2000-2016). [PDF]

Arch Public Health
de Andrade DP, Marques CM, de Andrade DCR, Lenzi L, Oliveira CS, de Figueiredo BC.   +5 more
europepmc   +1 more source

MIF as an oncogenic driver of low‐heterogeneity melanomas

Molecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran, Gabriela Athziri Sánchez‐Zuno, Rajan P. Kulkarni, Harriet M. Kluger, Richard Bucala   +4 more
wiley   +1 more source

Association between diabetes self-management education attendance, hospital admissions and mortality in type 2 diabetes: A cohort analysis protocol. [PDF]

Diabetes Obes Metab
Lewis GA, Hughes DM, Irving G, Wilding J, Hardy K.   +4 more
europepmc   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Identification of atopic dermatitis-associated diseases based on the National health and nutrition examination survey (NHANES) 2013-2018. [PDF]

Sci Rep
Liu Y, Chen X, Su Z, Wang X, Wang Y, Xue Y, Li Y, Gao X, Wang L, Hao J, Wang Y, Chu M.   +11 more
europepmc   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Therapeutic Challenges and Emerging Strategies for <i>T674I</i> and <i>PTPN11</i> Mutations in a <i>FIP1L1-PDGFRA</i>-Positive Myeloproliferative Neoplasm: A Case Report. [PDF]

Life (Basel)
Özkan SG, Kimiaei A, Safaei S, Karkucak M, Yenerel MN, Öztürkmen AY, Alp B, Özkan HA.   +7 more
europepmc   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

A Case of Tumor-to-Tumor Metastasis: Breast Carcinoma Metastatic to Oncocytic Carcinoma of Thyroid. [PDF]

Kans J Med
Gvazava N, Stevens TM, Rader RK.
europepmc   +1 more source

EXTENSIVE OCULO-PALPEBRAL NEOPLASM; EXCISION OF LIDS AND ENUCLEATION OF THE EYEBALL, FOLLOWED BY OCCLUSION OF THE ORBIT

, 1934
E. Puscariu
openalex   +1 more source