Results 271 to 280 of about 704,490 (345)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Case report: Resolution of lameness via compartmental resection of a malignant nerve sheath neoplasm of the median nerve in a dog. [PDF]

Front Vet Sci
Smith J, Kent M, Glass E, Davis G.
europepmc   +1 more source

Appendiceal Mucinous Neoplasm: An Unexpected Diagnosis in Abdominal Pain. [PDF]

Cureus
Pereira Soares I, Sampaio Mesquita A, Ramos L, Ussene E, Cunha F.   +4 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

More than 3 years of teleconsultations: A retrospective cohort study in specialized outpatient palliative care. [PDF]

Palliat Med
Veldeman S, Martin T, Wüeller J, Czaplik M, Follmann A.   +4 more
europepmc   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

Solid pseudopapillary neoplasm of the pancreas in an adolescent: A case report and review of the literature.

World J Gastrointest Oncol
Sapkota A, Paudel R, Pandey S, Bhatt N.
europepmc   +1 more source

Global burden of TBL cancer in older adults: the role of dietary factors (1990-2021). [PDF]

BMC Public Health
Zhang W, Zhang Y, Wei M, Zhu K, Wang X, Zhao Y, Shi J, Liu Z.   +7 more
europepmc   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Delayed malignant appendiceal fistula with ileal conduit following radical cystectomy: A case report. [PDF]

Urol Case Rep
Dalkin BH, Toskich BB, Colibaseanu DT, Erben Y, Lyon TD.   +4 more
europepmc   +1 more source