Results 281 to 290 of about 1,700,231 (391)

Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition

Leukemia, 2014
M. Sapienza, F. Fuligni, C. Agostinelli, C. Tripodo, S. Righi, M. Laginestra, A. Pileri, M. Mancini, M. Rossi, Francesca Ricci, A. Gazzola, F. Melle, C. Mannu, Francesca Ulbar, M. Arpinati, M. Paulli, T. Maeda, D. Gibellini, L. Pagano, N. Pimpinelli, M. Santucci, L. Cerroni, C. Croce, F. Facchetti, P. Piccaluga, S. Pileri   +25 more
semanticscholar   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Integrative Analysis of GEO Datasets and Mendelian Randomization Reveals a Potential Role ofISOC1 in Renal Cell Carcinoma. [PDF]

J Cancer
Wang J, Liu Y, Yan Z, Lu Q, Jian J, Liu X, Chen Z, Zheng Q, Wan S, Wang L.   +9 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

FDG PET/CT and Histopathologic Characteristics of Low-Grade Appendiceal Mucinous Neoplasm with Pseudomyxoma Peritonei. [PDF]

Diagnostics (Basel)
Liu LW, Chan HP, Shen DH, Lin CC.
europepmc   +1 more source

Myeloproliferative neoplasms with clinically relevant paroxysmal nocturnal hemoglobinuria: clinical correlations and outcomes

Priyansh Faldu, Rania Abdelaziz, Muhammad Yousuf, Animesh Pardanani, Mrinal Patnaik, Ayalew Tefferi, Naseema Gangat   +6 more
openalex   +1 more source

Genital Neoplasms [PDF]

Sexually Transmitted Infections, 1959
openaire   +2 more sources

Myeloproliferative neoplasm (MPN) symptom assessment form total symptom score: prospective international assessment of an abbreviated symptom burden scoring system among patients with MPNs.

Journal of Clinical Oncology, 2012
R. Emanuel, A. Dueck, H. Geyer, J. Kiladjian, S. Slot, S. Zweegman, P. T. te Boekhorst, S. Commandeur, H. Schouten, F. Sackmann, A. K. Kerguelén Fuentes, D. Hernández‐Maraver, H. Pahl, M. Griesshammer, F. Stegelmann, K. Doehner, T. Lehmann, Karin Bonatz, A. Reiter, F. Boyer, G. Étienne, J. Ianotto, D. Ranta, L. Roy, J. Cahn, C. Harrison, D. Radia, P. Muxí, N. Maldonado, C. Besses, F. Cervantes, P. Johansson, T. Barbui, G. Barosi, A. Vannucchi, F. Passamonti, B. Andreasson, M. Ferrari, A. Rambaldi, J. Samuelsson, G. Birgegard, A. Tefferi, R. Mesa   +42 more
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The Prevalence of Second Neoplasms in Patients with Non-Aldosterone Producing Adrenocortical Lesions. [PDF]

Int J Mol Sci
Tripolitsioti P, Spyroglou A, Violetis O, Konstantakou P, Chouliara E, Betsi G, Iliakopoulos K, Memi E, Bramis K, Kolomodi D, Xekouki P, Konstadoulakis M, Mastorakos G, Alexandraki KI.   +13 more
europepmc   +1 more source