Results 151 to 160 of about 2,228,127 (334)

Histologic Grading of Canine Mast Cell Tumor

Veterinary Pathology-Supplement, 2015
S. Sabattini, F. Scarpa, D. Berlato, Giuliano Bettini   +3 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Updates and challenges in pancreatic cytopathology

Human Pathology Reports
The World Health Organization (WHO) has recently introduced an international approach to standardize reporting of pancreaticobiliary cytopathology.
Patrick Yang, Liying Han, Zhongren Zhou
doaj   +1 more source

Molecular and clinical support for a four-tiered grading system for bladder cancer based on the WHO 1973 and 2004 classifications

Modern Pathology, 2015
B. V. Rhijn, M. Musquera, Liyang Liu, A. N. Vis, T. Zuiverloon, G. Leenders, W. Kirkels, E. Zwarthoff, E. Boevé, A. C. Jöbsis, B. Bapat, M. Jewett, A. Zlotta, T. Kwast   +13 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

High Grade Myeloid Neoplasm [PDF]

, 2020
openaire   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Performance of Magnetic Resonance Imaging-based Permeability Indices for Preoperative Glioma Grading [PDF]

Journal of Basic Research in Medical Sciences
Introduction: Due to the inherent limitations of histopathology as the gold standard method for glioma grading, in recent years, alternative methods, including methods based on imaging data, have been proposed for better glioma grading.
Sina Alikhani, Seyed Salman Zakariaee
doaj  

Low-grade appendiceal mucinous neoplasms: a case series

Journal of Surgical Case Reports
Abstract Appendiceal mucinous neoplasms, including low-grade appendiceal mucinous neoplasms (LAMNs), are infrequent but clinically relevant due to their potential progression to pseudomyxoma peritonei. Timely diagnosis and surgical intervention are critical to preventing complications.
Mohammed N AlAli, Jawad S Alnajjar, Mohamed S Essa, Arwa F Alrasheed, Maha AlAmodi, Nouf A Alromaih, Sadiq M Amer, Abdulbaset Al-Shoaibi, Ameen M Alshehri   +8 more
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source