Results 241 to 250 of about 74,828 (311)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Poorly differentiated clusters surpass tumor budding as novel prognostic factors in pancreatic cancer, especially in cases treated with neoadjuvant chemotherapy. [PDF]

BMC Gastroenterol
Uchihara D, Shimajiri S, Harada Y, Kumamoto K, Oe S, Miyagawa K, Nakamura K, Katafuchi E, Nuratdinova F, Honma Y, Shibata M, Harada M, Nakayama T.   +12 more
europepmc   +1 more source

Artificial Intelligence–Based Classification of Renal Oncocytic Neoplasms: Advancing From a 2-Class Model of Renal Oncocytoma and Low-Grade Oncocytic Tumor to a 3-Class Model Including Chromophobe Renal Cell Carcinoma

Katrina Collins, Shubham Innani, Kingsley Ebare, Mohammed Saad, Stephanie Siegmund, Sean R. Williamson, Fiona Maclean, Andrés Matoso, Ankur R. Sangoi, Michelle S. Hirsch, Dibson Gondim, Andrés Acosta, Bhakti Baheti, Spyridon Bakas, Muhammad T. Idrees   +14 more
openalex   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

The impact of tissue detection on diagnostic artificial intelligence algorithms in prostate digital pathology. [PDF]

Sci Rep
Boman SE, Mulliqi N, Blilie A, Ji X, Szolnoky K, Gudlaugsson E, Janssen EAM, Kjosavik SR, Asenjo J, Gambacorta M, Libretti P, Braun M, Kordek R, Łowicki R, Hotakainen K, Väre P, Pedersen BG, Sørensen KD, Ulhøi BP, Egevad L, Kartasalo K.   +20 more
europepmc   +1 more source

Distinguishing neuroendocrine tumor grade 3 from neuroendocrine carcinoma in gastroenteropancreatic high-grade neoplasms

Zandra Ankers, L. Samuel Hellgren, Adam Stenman, Jan Zedenius, C. Christofer Juhlin   +4 more
openalex   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Automatic segmentation and PI-RADS grading of prostate cancer for biparametric MRI. [PDF]

Front Med (Lausanne)
Li Y, Huang M, Wu Y, Zhang Y.
europepmc   +1 more source

Intracholecystic Papillary Neoplasm of the Gallbladder Neck With High‐Grade Dysplasia: A Diagnostic and Surgical Challenge

Pradeep Yadav, SS Yadav, Kshitiz Parajuli, Aron Neupane, Amit Sah, Neha Yadav   +5 more
openalex   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source