Results 221 to 230 of about 494,128 (290)

ELK1 promotes the progress of myeloid leukemia by hindering the differentiation of neutrophils. [PDF]

Exp Hematol Oncol
He Y, Zhou Y, Wen D, Guo R, Du J, Huang S, Dong Y.   +6 more
europepmc   +1 more source

Basal cell adenoma with S100 protein–positive “stroma”: a distinct triphasic salivary gland neoplasm characterized by CTNNB1 mutation [PDF]

Alena Skálová, Martina Bradová, Ján Laco, Tomáš Vaněček, Veronika Hájková, Petr Martínek, Marian Grendár, Giulia Querzoli, Ilmo Leivo, Michal Michal   +9 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Case Report: A case of intrahepatic papillary neoplasm of the bile duct with invasive carcinoma in a young patient and review of the literature. [PDF]

Front Oncol
Hu L, Wan H, Hong Y, Liang L, Wang Y.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Can BKPyV Infection Affect Neoplasm Transformation Among Kidney Transplant Recipients? A Case Series Study Report. [PDF]

J Clin Med
Poznański P, Wenta M, Augustyniak-Bartosik H, Rukasz D, Hałoń A, Kościelska-Kasprzak K, Kamińska D, Krajewska M.   +7 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Molecular Analysis Based on Fine-Needle Aspiration Washout Samples in Thyroid Nodules. [PDF]

Genes (Basel)
Fakı S, Aydın C, Polat ŞB, Karahmetli G, Ceylan AC, Altan M, Aksoy Altınboğa A, Çomçalı B, Topaloğlu O, Ersoy R, Çakır B.   +10 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

NFATC2::NUTM2A/B Fusions Characterize a Novel Indolent Myoepithelial-Like Neoplasm of the Lungs and Salivary Glands. [PDF]

Genes Chromosomes Cancer
Agaimy A, Dermawan JK, Rios E, Meidenbauer N, Dimmler A, Stoehr R, Antonescu CR.   +6 more
europepmc   +1 more source