Results 191 to 200 of about 310,430 (355)

Senescence‐Inducing Therapy Sequential NIR‐II Mild Photothermal/Senolytic Therapy of Triple Negative Breast Cancer

Advanced Science, EarlyView.
Targeting triple‐negative breast cancer remains challenging due to limited therapies and drug resistance. A sequential theranostic strategy combining palbociclib‐induced senescence (enhancing heat sensitivity via HSP70 downregulation) with an NIR‐II nanoplatform (IQ NPs) for mild photothermal therapy (PTT) and quercetin‐mediated senolysis is developed.
Liya Yu, Yehui Kang, Mengdie Yu, Yuejia Ding, Yang Chen, Qingyuan Wu, Yu Cai, Huiyu Liu, Zhenye Lv   +8 more
wiley   +1 more source

Giant Cell Tumor of the Tendon Sheath: Case Series and Review of Literature. [PDF]

J Orthop Case Rep
Parakh NK, Kumar SK, Jain S, Shah P.
europepmc   +1 more source

Colorectal cancer: cross-sectional imaging for staging of primary tumor and detection of local recurrence.

AJR. American journal of roentgenology, 1991
R. Thoeni
semanticscholar   +1 more source

Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular Carcinoma

Advanced Science, EarlyView.
The limited understanding of IGFR pathway activation hinders its clinical application in HCC. Here, IGFRIL is identified as a novel non‐coding activator of the IGF1R, which recruits PTBP1 to destabilize IGFBP3 mRNA and activates IGF1R, and proposes IGFRIL as a novel actionable target for HCC patients.
Jing Zhang, Chengming Gao, Haibei Li, Yuying Chen, Liting Yang, Qian Jin, Lan Feng, Xia Wang, Xinyi Liu, Hongxia Chen, Rong Ye, Yuanchao Xue, Huiyun Wang, Musheng Zeng, Ming Yang, Huaiqiang Ju, Chengzhi Gao, Guangming Zhou, Qi Zhang, Qian Zhang, Geng Qin, Yuanfeng Li, Yahui Wang, Aiqing Yang, Anfeng Si, Qingfeng Song, Fuchu He, Pengbo Cao, Gangqiao Zhou   +28 more
wiley   +1 more source

Tamoxifen for nodal recurrence of serous borderline ovarian tumour - a case report. [PDF]

Gynecol Oncol Rep
Guarneri A, Zeng X, Ribeiro R, Leung SOA, Mandilaras V, Tessier-Cloutier B, Fu L, Ton Nu TN, Richer L, Gilbert L, Bernard L.   +10 more
europepmc   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

Advanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou, Cheng‐Wei Ju, Nicholas A. Egan, Yanjun Wei, Yunfei Wang, Minghao Dang, Tianyi Zhou, Leilei Shi, Ningbo Zheng, Si Chen, Ashley M. Guerrero, Xiaofang Liang, Wanfu Wu, Areej Akhtar, Chitra Dhiman, Debanwita Roy Burman, Andro E. Gerges, Mason D. Flores, Han Li, Li‐Sheng Zhang, Marleen Kok, Xiaobo Mao, Linghua Wang, Qin Feng, Yiwen Chen, Sanghoon Lee, Daniel J. McGrail, Nidhi Sahni, Chuan He, Amir A. Jazaeri, Weiyi Peng   +30 more
wiley   +1 more source

Histologic grade and STAS as key predictors of distant recurrence in resected early-stage lung adenocarcinoma: a single-center study. [PDF]

Front Oncol
Bonis A, Pagliarini G, Comacchio GM, Mammana M, Pezzuto F, Verzeletti V, Pellizzer E, Berni A, Silvestrin S, Cannone G, Faccioli E, Rebusso A, Schiavon M, Nicotra S, Dell'Amore A, Calabrese F, Rea F.   +16 more
europepmc   +1 more source

Bilateral carcinomas of the breast with local recurrence: analysis of genetic relationship of the tumors

Modern Pathology, 2004
P. Regitnig, F. Ploner, Martina Maderbacher, S. Lax   +3 more
semanticscholar   +1 more source

Argon plasma coagulation therapy after submucosal injection of normal saline solution for local recurrence of large nonampullary duodenal neoplasm

VideoGIE, 2016
Miyabi Miura, Hajime Takatori, Kazuya Kitamura, Tatsuya Yamashita, Shuichi Kaneko, Tomoyuki Hayashi   +5 more
openaire   +4 more sources

Engineering Bacteria as Living Therapeutics in Cancer Therapy

Advanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen, Jiaqi Chen, Yixuan Chen, Wenxuan Yuan, Jiao Zhang, Guoqing Wang, Zhuojun Dai   +6 more
wiley   +1 more source