Results 221 to 230 of about 310,430 (355)

Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning   +11 more
wiley   +1 more source

No difference in prognosis between atypical intradermal smooth muscle neoplasms and dermal leiomyosarcoma: Local recurrence, metastasis, and overall survival in a nationwide cohort of 423 patients [PDF]

open access: yesJournal of the American Academy of Dermatology
Abebe, Kiya   +13 more
openaire   +3 more sources

Near‐Infrared‐Responsive Digital PCR‐Assisted Renal Cancer Exosomal miRNAs Insights and Regulation of Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
A near‐infrared‐responsive digital Polymerase Chain Reaction technique with triple‐color coding profiles renal cancer exosomal microRNA biomarkers and their impact on macrophage polarization. Engineered miR‐34‐loaded exosomes via electroporation saturate molecular sponges, downregulating STAT3 in recipient macrophages to prolong M2 polarization. Stable
Lexiang Zhang   +11 more
wiley   +1 more source

Endoscopic submucosal dissection for colorectal neoplasms: Risk factors for local recurrence and long-term surveillance

open access: yesEndoscopic submucosal dissection for colorectal neoplasms: Risk factors for local recurrence and long-term surveillance
2024年度
openaire  

Intravenous iRGD‐Guided, RBC‐Membrane Camouflaged Lactococcus Lactis Remodels Cold NSCLC and Enhances PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study presents an engineered probiotic platform, iRGD‐mRBC@FOLactis, combining red blood cell membrane cloaking and tumor‐penetrating peptide iRGD for enhanced PD‐1 blockade. The platform improves tumor targeting, immune cell activation and therapeutic efficacy in lung cancer, demonstrating significant promise in overcoming PD‐1/PD‐L1 therapy ...
Chen Chen   +9 more
wiley   +1 more source

Mesenchymal phosphaturic tumour: early detection of recurrence

open access: yesBMJ Case Reports, 2014
F. Allevi   +3 more
semanticscholar   +1 more source

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