Results 231 to 240 of about 310,430 (355)

Hypoxia‐Induced PRMT1 Lactylation Drives Vimentin Arginine Asymmetric Dimethylation in Tumor Metastasis

Advanced Science, EarlyView.
Hypoxia triggers lactylation of PRMT1 at K134/K145, enhancing its methyltransferase activity to asymmetrically dimethylate vimentin R64. This post‐translational cascade promotes vimentin filament assembly, cytoskeletal remodeling, and tumor metastasis, with PRMT1 inhibition (MS023) reducing metastatic colonization.
Jia Zhou, Shuying Qiu, Xia Yang, Yan Wu, Xinxia Yao, Hangqi Hu, Jingfeng Luo, Chandra Sugiarto Wijaya, Lingfeng Ma, Xiaojun Long, Lingna Xu, Jinquan Liu, Chaoqun Wang, Yibin Pan, Xiaona Chen, Hongchuan Jin, Xian Wang   +16 more
wiley   +1 more source

Malignant cutaneous adnexal neoplasms with distant brain metastasis: an aggressive behavior. Illustrative cases. [PDF]

J Neurosurg Case Lessons
Vargas-Urbina J, Martinez-Silva R, Rojas-Panta G, Ponce-Manrique G, Flores-Castillo J, Anicama-Lima W.   +5 more
europepmc   +1 more source

Integrating Metabolic Modulation and Nanomedicine for Cancer Immunotherapy

Advanced Science, EarlyView.
Metabolic rewiring in cancer is mapped across glucose, amino acid, lipid, nucleotide, and mitochondrial pathways, with emphasis on immune regulation. The review integrates mechanisms linking these pathways to tumor progression and therapy resistance, and profiles nanomaterial platforms that both deliver therapeutics and actively reprogram ...
Xiaosu Zhou, Ruibing Deng, Zunde Liao, Xiaoyu Huang, Junting Huang, Hanlou Yang, Kam W. Leong, Yiling Zhong   +7 more
wiley   +1 more source

Primary cutaneous mucinous carcinoma in unusual location: A case report. [PDF]

Int J Surg Case Rep
Atallah A, Bacha D, Guelbi M, Hajri M, Megdiche S, Omrani S.   +5 more
europepmc   +1 more source

Phyllodes Tumor of the Breast: Histopathologic Features, Differential Diagnosis, and Molecular/Genetic Updates.

Archives of Pathology & Laboratory Medicine, 2016
Yanhong Zhang, C. Kleer
semanticscholar   +1 more source

Magnetized Cell‐Scaffold Constructs for Bone Tissue Engineering: Advances in Fabrication and Magnetic Stimulation

Advanced Science, EarlyView.
This review highlights the synthesis and applications of magnetized cells (MCs) and magnetized scaffolds (MSs) in advancing bone tissue engineering strategies. It further demonstrates how magnetic particles (MPs) improve scaffold properties and how external magnetic fields enhance mesenchymal stem cell adhesion, proliferation, and osteogenic ...
Elio Cinar SanSegundo, Mohammad J. Mirzaali, Lidy E. Fratila‐Apachitei, Amir A. Zadpoor   +3 more
wiley   +1 more source

Diagnostic and management challenges in a partially infarcted borderline phyllodes tumor in an adolescent female: A case report and review of literature. [PDF]

World J Clin Pediatr
Suschana E, Sta Ines FM, Manrai P, Koelliker S, Gass JS, Tseng YA.   +5 more
europepmc   +1 more source

Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot

Advanced Science, EarlyView.
In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai, Xiaoyi Shi, Xiao Liu, Xiaotong Gu, Wenting Li, Xiangjun Chen, Wei Hong   +6 more
wiley   +1 more source

Recurrent Malignant Phyllodes Tumor of the Breast: A Case Report. [PDF]

Clin Case Rep
Akhtar AN, Ali A, Gohar A, Ali M, Rehman A, Bajwa FA, Haseeb M, Ahmad MH.   +7 more
europepmc   +1 more source

Strategic Timing of Gene Silencing: Cellular Kinetics‐Based Administration of siRNA for Optimized Photothermal Cancer Treatment

Advanced Science, EarlyView.
Coordinating therapy with gene expression kinetics emerges as a key strategy for maximizing nanomedicine efficacy in aggressive cancers. A hybrid nanocarrier delivering HSP70‐targeting siRNA demonstrates this chronotherapeutic principle through systematic cellular profiling.
Tianliang Fang, Li Li, Ziyad Tariq Muhseen, Lucas A. Lane, Huiming Cai, Christopher J. Butch, Yiqing Wang   +6 more
wiley   +1 more source