Results 271 to 280 of about 319,917 (352)

Insights From the AO Spine Knowledge Forum Tumor Registries: Advancing the Understanding and Management of Primary Spine Tumors Through International Multicentric Collaboration. A Narrative Review. [PDF]

open access: yesGlobal Spine J
Cecchinato R   +24 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang   +2 more
wiley   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu   +8 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

open access: yesAdvanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen   +10 more
wiley   +1 more source

Redox‐Programmed Activation of a Dual‐Modal Probe for High‐Fidelity Tumor Delineation and Image‐Guided Surgery

open access: yesAdvanced Science, EarlyView.
This study presents a glutathione (GSH)‐activatable dual‐modality probe (GAP9) with a redox‐tuned activation window for precise tumor detection. It remains quenched (“OFF”) in normal tissue yet activates specifically in tumors for T1‐weighted magnetic resonance imaging (MRI) preoperative mapping and near‐infrared II (NIR‐II) fluorescence intraoperative
Haohao Yan   +4 more
wiley   +1 more source

Characteristics, treatment, and outcome of recurrent gastro-oesophageal adeno-carcinoma after perioperative chemotherapy and radical resection. [PDF]

open access: yesActa Oncol
Larsen AC   +8 more
europepmc   +1 more source

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