Results 51 to 60 of about 35,449 (253)

Pediatric Langerhans Cell Histiocytosis of Bone: A systematic review of the unknown mechanism of self-healing

open access: yesPediatric Hematology Oncology Journal
Background/objectives: Langerhans cell histiocytosis (LCH) is a rare pediatric neoplasm frequently involving bone. While various therapeutic strategies exist, including surgery and systemic therapy, some lesions—particularly unifocal bone lesions—have ...
Dana Ashkenazi Lustig   +2 more
doaj   +1 more source

Interventional treatment of renal angiomyolipoma:immediate results and clinical and radiological follow-up of 4.5 years [PDF]

open access: yes, 2015
Background Renal angiomyolipoma is rare, but many of these patients may have an acute debut with severe bleeding. These patients need urgent treatment with interventional embolization as an attractive option.
Andersen, Poul Erik   +4 more
core   +2 more sources

Recent Advances of Slip Sensors for Smart Robotics

open access: yesAdvanced Materials Technologies, EarlyView.
This review summarizes recent progress in robotic slip sensors across mechanical, electrical, thermal, optical, magnetic, and acoustic mechanisms, offering a comprehensive reference for the selection of slip sensors in robotic applications. In addition, current challenges and emerging trends are identified to advance the development of robust, adaptive,
Xingyu Zhang   +8 more
wiley   +1 more source

A Case of Congenital Brainstem Oligodendroglioma: Pathology Findings and Review of the Literature

open access: yesCase Reports in Neurological Medicine, 2017
Congenital and perinatal primary brain neoplasms are extremely rare. Brainstem neoplasms in the perinatal and neonatal period are typically of high-grade nature and have poor prognoses with survival rates of less than 2 years from diagnosis.
Stefan Kostadinov, Suzanne de la Monte
doaj   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

open access: yesAdvanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen   +4 more
wiley   +1 more source

Treatment sequencing strategy for hepatic epithelioid haemangioendothelioma [PDF]

open access: yes, 2015
Background The biology of hepatic epithelial haemangioendothelioma (HEHE) is variable, lying intermediate to haemangioma and angiosarcoma. Treatments vary owing to the rarity of the disease and frequent misdiagnosis.
Abdalla, Eddie   +7 more
core   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui   +14 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

Burned-Out Testicular Tumour: An Unusual Presentation

open access: yesGazeta Médica
Although being relatively uncommon, testicular primary germ cell tumours represent most of testicular tumours in young and middle-aged men. Metastatic disease accounts for up to ten percent of initial presentation. A 31-year-old man presented with a two-
Nuno Santos Sousa   +5 more
doaj   +1 more source

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