Results 171 to 180 of about 680,873 (331)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Survival of patients with mucosal melanoma in Cali, Colombia: a retrospective cohort study

BMC Cancer
Background Mucosa melanoma is a rare condition with aggressive behavior and a less favorable prognosis compared to cutaneous melanoma. The objective of this study was to estimate the overall survival and clinical outcomes of patients diagnosed with ...
Ana M. García, Luis G. Parra-Lara, Diana M. Mendoza-Urbano, Juan C. Bravo, Ángela Zambrano Harvey   +4 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

New staging classification for pancreatic neuroendocrine neoplasms combining TNM stage and WHO grade classification [ ]

, 2021
Min Wang, Ding Ding, Tingting Qin, Hebin Wang, Yahui Liu, Jianhua Liu, Jun Liu, Hang Zhang, Junfang Zhao, Chien‐Hui Wu, Ammar A. Javed, Christopher L. Wolfgang, Shiwei Guo, Qingmin Chen, Weihong Zhao, Wei Shi, Feng Zhu, Xingjun Guo, Xu Li, Ruizhi He, Simiao Xu, Barish H. Edil, Yu‐Wen Tien, Gang Jin, Lei Zheng, Jing He, Renyi Qin   +26 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

TNM Staging of Neoplasms of the Endocrine Pancreas: Results From a Large International Cohort Study [PDF]

, 2012
Guido Rindi, Massimo Falconi, Catherine Klersy, Luca Albarello, Letizia Boninsegna, Markus W. Büchler, C. Capella, Martyn Caplin, Anne Couvelard, Claudio Doglioni, Gianfranco Delle Fave, L. Fischer, Giuseppe Fusai, Wouter W. de Herder, Henning Jann, Paul Komminoth, Ronald R. de Krijger, Stefano La Rosa, Tu Vinh Luong, Ulrich F. Pape, Aurel Perren, Philippe Ruszniewski, Aldo Scarpa, Anja Schmitt, Enrico Solcia, Bertram Wiedenmann   +25 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Incorporation of the 2008 WHO into 2008/2020 ECMP/CLMP Classification for Staging and Prog-nosis Assessment of JAK2, MPL, TPO, MPL and CALR Mutated Myeloproliferative Neoplasms: From Dameshek to Vainchenker and Michiels 1940 - 2020: A Historical Appraisal and Novel Therapeutic Implications

, 2020
Jan Michiels, Wilfried Schroyens, Konnie M. Hebeda, King H. Lam, Francisca Valster, Vincent Potter, Katrien Schelfout, Hendrik De Raeve   +7 more
openalex   +1 more source

Application of miniprobe sonography in the local staging of earlier stage upper gastrointestinal epithelial neoplasm: A four‐year experience in a single center [PDF]

, 2018
Wen‐Hung Hsu, Chao‐Hung Kuo, Meng‐Chieh Wu, Yu‐Chung Su, Chiao‐Yun Chen, Jaw‐Yuan Wang, Yao‐Hsiang Shih, Chien‐Yu Lu, Deng‐Chyang Wu, Fang‐Jung Yu   +9 more
openalex   +1 more source