Results 181 to 190 of about 163,967 (338)

Cytogenetic Evolution in Myeloid Neoplasms at Relapse after Allogeneic Hematopoietic Cell Transplantation: Association with Previous Chemotherapy and Effect on Survival

, 2017
Natalie Ertz-Archambault, Heidi Kosiorek, James L. Slack, Melissa L. Lonzo, Patricia T. Greipp, Nandita Khera, Katalin Kelemen   +6 more
openalex   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

Paediatric blastic plasmacytoid dendritic cell neoplasm: a single-centre case series of 18 children and review of the literature. [PDF]

Ann Hematol
Zhang ZX, Zhang L, Lu AD, Zhang LP, Jia YP, Wang F, Zeng HM.   +6 more
europepmc   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

Avapritinib in the treatment of systemic mastocytosis with associated acute myeloid leukemia after poor graft function following allogeneic hematopoietic stem cell transplantation: a case study and review of the literature. [PDF]

Front Oncol
Mi R, Li X, Chen L, Wang L, Ma Y, Fu Y, Wei X.   +6 more
europepmc   +1 more source

Genetic features and outcomes of allogeneic transplantation in patients with WT1-mutated myeloid neoplasms

, 2023
Anmol Baranwal, Rami Basmaci, Rong He, David S. Viswanatha, Patricia T. Greipp, Hemant S. Murthy, James M. Foran, Jeanne Palmer, William J. Hogan, Mark R. Litzow, Mehrdad Hefazi, Abhishek A. Mangaonkar, Mithun Vinod Shah, Aref Al‐Kali, Hassan B. Alkhateeb   +14 more
openalex   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Clonal hematopoiesis and subsequent venous thromboembolism among survivors of autologous transplantation for lymphoma. [PDF]

J Natl Cancer Inst
Gangaraju R, Chen Y, Hageman L, Bosworth A, Ross E, Francisco L, Singh P, Richard MA, Yan C, Kalra R, Cheng C, Armenian SH, Forman SJ, Bhatia R, Bhatia S.   +14 more
europepmc   +1 more source

Myeloid Neoplasms Following Solid Organ Transplantation [PDF]

American Journal of Clinical Pathology, 2017
Bin Wu, Kimberly Ingersoll, Rachel Jug, Lian-he Yang, Catherine Luedke, Amanda Lo, Pu Su, Xin Liu, Catherine Rehder, Jerald Gong, Chuanyi Mark Lu, Endi Wang   +11 more
openaire   +1 more source

Cutaneous and mucosal neoplasms in bone marrow transplant recipients [PDF]

, 1990
Michael Lishner, Bruce Patterson, Rita A. Kandel, Gillian Fyles, J. E. Curtis, J. Meharchand, Mark D. Minden, Hans A. Messner   +7 more
openalex   +1 more source