Neoplasm Transplantation Inhibition by Uninvolved Lymph Tissue [PDF]
HETEROLOGOUS transplantation of human neoplasms into the cheek pouch of the syrian hamster (Mesocricetus auratus) was first reported in 1951 (ref. 1). The uniqueness of the pouch as a site for transplantation results from the alymphatic structure and the very slow diffusion of large molecules out of the pouch area2.
Burton V. Caldwell, Paul A. Wright
openaire +4 more sources
Transduction-Transplantation Mouse Model of Myeloproliferative Neoplasm [PDF]
Transduction-transplantation is a quick and efficient way to model human hematologic malignancies in mice. This technique results in expression of the gene of interest in hematopoietic cells and can be used to study the gene's role in normal and/or malignant hematopoiesis.
Nguyen, Thanh Kim+2 more
openaire +5 more sources
Numerous prognostic indexes have been developed in hematological diseases based on patient characteristics and genetic or molecular assessment. However, less attention was paid to more accessible parameters, such as neutrophils, lymphocytes, monocytes ...
Olga Mulas+5 more
doaj +1 more source
Resolution of the clinical features of tyrosinemia following orthotopic liver transplantation for hepatoma [PDF]
The clinical history before transplantation and subsequent clinical and biochemical course of 3 children and one adult with hereditary tyrosinemia treated by orthotopic hepatic transplantation is described.
Berger+22 more
core +1 more source
Long-term results after liver transplantation for primary hepatic epithelioid hemangioendothelioma [PDF]
Background: Hepatic epithelioid hemangioendothelioma (PHEHE) is a multifocal, low-grade malignant neoplasia characterized by its epithelial-like appearance and vascular endothelial histogenesis.
American Joint Committee on Cancer+21 more
core +2 more sources
Treatment of a mixed acinar-endocrine carcinoma with uptake on 68Gallium-DOTATOC positron emission tomography-computed tomography : a case report [PDF]
The case of a 35-year old female patient with a diagnosis of metastatic mixed acinar-endocrine carcinoma (MAEC) is investigated in the present study.
De Both, Anneleen+5 more
core +2 more sources
Malignant neoplasms following bone marrow transplantation [PDF]
We undertook an analysis of 2,150 recipients of bone marrow transplant (BMT) at the University of Minnesota to determine the incidence of post- BMT malignant neoplasms (MNs). Fifty-one patients developed 53 MNs, compared with 4.3 expected from general population rates (standardized incidence ratio [SIR], 11.6, 95% confidence interval [CI], 8.2–14.5 ...
Michael Steinbuch+8 more
openaire +3 more sources
Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm. [PDF]
The Notch signaling pathway contributes to the pathogenesis of a wide spectrum of human cancers, including hematopoietic malignancies. Its functions are highly dependent on the specific cellular context. Gain-of-function NOTCH1 mutations are prevalent in
Chang, Yuan-I+20 more
core +1 more source
Blastic plasmacytoid dendritic cell neoplasm: Genomics mark epigenetic dysregulation as a primary therapeutic target [PDF]
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy for which there is still no effective B therapy.
Abate F.+30 more
core +2 more sources
Decision Support System for Renal Transplantation [PDF]
The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the paper develops a prediction model that identifies factors that determine the probability of success of renal ...
arxiv +1 more source