Results 191 to 200 of about 159,123 (340)

Patient Characteristics and Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

, 2023
Muzaffar H. Qazilbash, Hina Khan, Denái R. Milton, Oren Pasvolsky, Mark R. Tanner, Uday Popat, Partow Kebriaei, Chitra Hosing, Issa F. Khouri, Katayoun Rezvani, Yago Nieto, Betül Oran, Samer A. Srour, Neeraj Saini, Amanda Olson, Sairah Ahmed, Gheath Alatrash, Gabriela Rondón, Marina Konopleva, Richard E. Champlin, Elizabeth J. Shpall, Qaiser Bashir, Naveen Pemmaraju   +22 more
openalex   +1 more source

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

Advanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma   +17 more
wiley   +1 more source

Allogeneic haematopoietic cell transplantation in advanced systemic mastocytosis in new era: A CIBMTR study. [PDF]

Br J Haematol
Ustun C, Zhang MJ, Peterson A, Baek A, Agha M, Alkhateeb H, Chhabra S, Coltoff A, de Lima M, Gandhi A, Ho V, Kassim A, Lin A, Gowda L, Borthakur G, DeAngelo DJ, McGuirk J, Mensah F, Nadiminti KV, Nishihori T, Pantin J, Trunk A, Uberti J, Marcucci G, Gotlib J, Akin C, Hamadani M, Pullarkat V, Valent P, Grunwald M, Juckett M, Oran B, Saber W, Burns LJ.   +33 more
europepmc   +1 more source

Brazilian Society of Bone Marrow Transplantation (SBTMO) Consensus on Chronic Myeloproliferative Neoplasms

, 2023
Marcos Paulo Colella, Antônio Vaz de Macedo, Gustavo Machado Teixeira, Andreza Alice Feitosa Ribeiro, Afonso Celso Vigorito, Vaneuza Araújo Moreira Funke   +5 more
openalex   +2 more sources

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

Advanced Science, EarlyView.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li, Jinlin Liao, Yuxi Zhang, Zifu Yao, Junxin Huang, Kejia Wu, Lu Li, Yiling Peng, Haili Zhu, Xue Hong, Xi Liu, Lili Zhou, Fan Fan Hou, Haiyan Fu, Youhua Liu   +14 more
wiley   +1 more source

Impact of the addition of antithymocyte globulin to post-transplantation cyclophosphamide in haploidentical transplantation with peripheral blood compared to post-transplantation cyclophosphamide alone: A retrospective study on behalf of the Cellular Therapy and Immunobiology Working Party of the European Society for Blood and Marrow Transplantation. [PDF]

Br J Haematol
Capes A, Mooyaart JE, Blaise D, Bramanti S, Kwon M, Mohty M, Chevallier P, Vydra J, Reményi P, Forcade E, López Corral L, Itälä-Remes M, Bazarbachi A, Derenzini E, Hoogenboom JD, Kuball J, Battipaglia G, Malard F, Ruggeri A.   +18 more
europepmc   +1 more source

A Single Center Retrospective Study on the Efficacy of Haploidentical Hematopoietic Stem Cell Transplantation in Patients with Myeloid Neoplasms over 50 Years Old

, 2023
Meng Liu, Xiaoli Wang, Yi Luo, Yanmin Zhao, Jian Yu, Xiaoyu Lai, Lizhen Liu, Huarui Fu, Weiyan Zheng, Jie Sun, Jingsong He, Yi Zhao, Guoqing Wei, Zhen Cai, He Huang, Jimin Shi   +15 more
openalex   +1 more source

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Prevalence and risk of progression of pancreatic cystic lesions in immunosuppressed patients: A systematic review and meta-analysis. [PDF]

World J Transplant
Kießler M, Friess H, Assfalg V.
europepmc   +1 more source

Therapeutic Approaches for Blastic Plasmacytoid Dendritic Cell Neoplasm: Allogeneic Hematopoietic Cell Transplantation and Novel Therapies

, 2019
Mohamed A. Kharfan‐Dabaja, Naveen Pemmaraju, Mohamad Mohty   +2 more
openalex   +1 more source