Results 201 to 210 of about 159,123 (340)

Application Gene Variation Detection before and after Hematopoietic Stem Cell Transplantation to Predict the Relapse of Hematopoietic Neoplasm Patients after Transplantation: Retrospective Data from a Single Center in China

, 2023
Jia Liu, Peiyan Kong, Lidan Zhu, Shichun Gao, Lu Wang, Huanfeng Liu, Ting Chen, Yimei Feng, Yuqing Liu, Lei Gao, Xi Zhang   +10 more
openalex   +1 more source

Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8

Advanced Science, EarlyView.
Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong, Zhen Guo, Yu‐Lan Ma, Ming‐Yu Wang, Hai‐Yang Ni, Pan Wang, Wen‐Jun Qiu, En‐Gui Wang, Zhou Li, Zheng Yang, Bo Shen, Qi‐Zhu Tang   +11 more
wiley   +1 more source

Lung transplant complicated with unexpected neoplasm in explanted lungs: A difficult challenge to manage

, 2019
S.C. Silva, Nicole Murinello, Sara Alfarroba, Ana Sofia Santos, Paulo Calvinho, Luís Curvo‐Semedo   +5 more
openalex   +1 more source

Nanographene Oxide Attenuates Acute GVHD by Modulating Macrophage Polarization in a Xenogeneic Mouse Model

Advanced Science, EarlyView.
Nanographene oxide (NGO) attenuates graft‐versus‐host disease (GVHD) severity by inhibiting STAT1‐mediated M1 macrophage polarization and suppressing T‐cell activation. NGO‐primed macrophages (NGO‐Mac) further enhance regulatory T‐cell induction via IL‐10. Both NGO and NGO‐Mac therapies mitigate inflammation and immune pathology, offering cell‐free and
Aaron Yu, Hyun Sung Park, Dong‐Hoon Chae, Jae Han Park, Jiyoung Heo, Keonwoo Cho, Jiho Kim, Hyewon Lee, Sueyeon Jee, Chanwoo Kim, Soon Won Choi, Jaechul Ryu, Eun‐Hye Hur, Yunsuk Choi, Eun‐Ji Choi, Mi‐Kyung Oh, Hwa‐Yong Lee, Je‐Hwan Lee, Kyung‐Rok Yu   +18 more
wiley   +1 more source

Pre-existing oncohematological disease in kidney transplant recipients: impact on graft survival, acute rejection, and long-term clinical outcomes. [PDF]

Front Immunol
Mella A, Clari R, Deiana V, Giraudi R, Giovinazzo G, Gallo E, Dolla C, Lavacca A, Manzione AM, Fop F, Allesina A, Cavallo F, Bringhen S, Ferrero D, Mina R, Tarella C, Bruno B, Mariano F, Biancone L.   +18 more
europepmc   +1 more source

Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond

Advanced Science, EarlyView.
Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao, Yunfan Lin, Pei Lin, Ye Lu, Jiarong Zheng, Xu Chen, Zihao Zhou, Li Cui   +7 more
wiley   +1 more source

Impact of cryotherapy on incidence and severity of oral mucositis in hematopoietic stem cell transplantation: retrospective observational study. [PDF]

Sci Rep
Piotrowska O, Zuchmańska A, Kulig P, Michowski T, Szulc J, Skórka P, Dorsz D, Machaliński B, Milczarek S.   +8 more
europepmc   +1 more source

Efficacy of the Pan-Bcl-2 Inhibitor (Obatoclax) As a Single Agent to Treat Myeloproliferative Neoplasm in JAK2V617F Murine Transplantation Model

, 2019
Thiago Mantello Bianco, Juan Luiz Coelho‐Silva, Diego A. Pereira‐Martins, Priscila Santos Scheucher, Isabel Weinhäuser, Antonio Bruno Alves Silva, Cleide Lucia Silva, Ann Mullally, Susumu Kobayashi, Eduardo Magalhães Rego, Fabı́ola Traina, Lorena Lôbo Figueiredo-Pontes   +11 more
openalex   +1 more source

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

Advanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao, Yifu Shen, Zhihui Xiao, Zhenbo Han, Xu Liu, Ao Cai, Yanan Tian, Guang Lian, Wenya Ma, Yining Liu, Rui Gong, Hanjing Li, Xiuxiu Wang, Zhongyu Ren, Naufal Zagidullin, Lei Yu, Ye Tian, Yu Liu, Zhenwei Pan, Baofeng Yang, Benzhi Cai   +20 more
wiley   +1 more source

Targeting oncogenic acetyltransferase NAT10 to overcome anti-PD-1 resistance in nasopharyngeal carcinoma. [PDF]

J Immunother Cancer
Zhao Y.
europepmc   +1 more source