Results 221 to 230 of about 76,990 (339)

MYC/TET3‐Regulated TMEM65 Activates OXPHOS‐SERPINB3 Pathway to Promote Progression and Cisplatin Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) remains a major challenge in breast cancer management as it lacks effective therapeutic targets. This study uncovers that MYC/TET3‐regulated mitochondrial inner‐membrane protein TMEM65 promotes TNBC progression and cisplatin resistance by activating the OXPHOS‐SERPINB3 pathway and reveals TMEM65 as a potential ...
Yin‐Ling Zhang, Min‐Ying Huang, Shao‐Ying Yang, Jia‐Yang Cai, Qian Zhao, Fang‐Lin Zhang, Xin Hu, Zhi‐Min Shao, Li Liao, A‐Yong Cao, Da‐Qiang Li   +10 more
wiley   +1 more source

Accessing the Impacts of the Calculated Panel Reactive Antibody Value on a Lung Transplant Waitlist: A Latin American Experience. [PDF]

J Clin Med
Dos Santos SL, Dos Reis FP, Abdalla LG, Fernandes LM, Okuno EA, Bueno Camargo PCL, Carraro RM, Campos SV, Teixeira RHOB, Pêgo-Fernandes PM.   +9 more
europepmc   +1 more source

Insulin, glucagon, peptide and amino acid levels following liver transplantation [PDF]

, 1987
Conte, D, Francavilla, A, Kam, I, Lynch, S, Polimeno, L, Reale, L, Starzl, TE, Tedane, E, Todo, S, Van Thiel, DH   +9 more
core  

Reexamining the association of body mass index with overall survival outcomes after liver transplantation [PDF]

, 2017
Alhamad, Tarek, Carlsson, Nils P, Chang, Su-Hsin, Chapman, William C, Colditz, Graham A, Doyle, Maria B, Garonzik-Wang, Jacqueline M, Liu, Xiaoyan, Park, Yikyung, Wellen, Jason R   +9 more
core   +2 more sources

QSOX2‐Mediated Disulfide Bond Modification Enhances Tumor Stemness and Chemoresistance by Activating TSC2/mTOR/c‐Myc Feedback Loop in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
High QSOX2 enhances stemness, drug resistance, and metastasis of ESCC cells. QSOX2‐mediated disulfide bond modification activates mTOR/c‐Myc signaling. CAFs‐secreted IGF‐1 drives mTOR/c‐Myc/QSOX2 positive feedback loop. Combining Ebselen, rapamycin, and cisplatin induces tumor dormancy in mice.
Wo‐Ming Chen, Xiao‐Ping Zhang, Xiao Sun, Hai‐Cheng Liu, Yuan‐Yuan Yan, Xue Wei, Yu Liang, Yue Feng, Zhengjie Chen, Yongxu Jia, Chen Jiang, Qian Yan, Lei Li   +12 more
wiley   +1 more source

Liver transplantation for the treatment of neuroendocrine liver metastases. [PDF]

Front Surg
Orozco G, Ramaiah D, Cracco A, Desai S, Gedaly R.   +4 more
europepmc   +1 more source

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Advanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai   +10 more
wiley   +1 more source

Induction of mammary neoplasms in the SPrague-Dawley rat by 430 keV neutrons and X-rays [PDF]

, 1980
Chmelevsky, D., Kellerer, Albrecht M., Shellabarger, C. J.   +2 more
core   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Telomere biology disorders in lung transplantation: Clinical challenges and management strategies. [PDF]

JHLT Open
Mesli F, Philippot Q, El Husseini K, Bunel V, Kannengiesser C, Debray MP, Guyard A, Crestani B, Ba I, Borie R.   +9 more
europepmc   +1 more source