Results 231 to 240 of about 163,967 (338)

Alternative 5-Azacitidine 5-Day 100 mg/m² Dosage Shows Non-Inferiority to Classical Schedule for Myelodysplastic Neoplasm (MDS) and Chronic Myelomonocytic Leukaemia (CMML) Treatment. [PDF]

EJHaem
Tsilimidos G, Martins F, Costanza M, Gavillet M, Blum S.   +4 more
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Post-Transplant Outcomes in Patients with Previously Treated Extrahepatic Malignancies Undergoing Living Donor Liver Transplantation. [PDF]

Ann Transplant
Kim A, Hwang S, Ahn CS, Moon DB, Ha TY, Song GW, Jung DH, Park GC, Kang WH, Yoon YI, Lee SG.   +10 more
europepmc   +1 more source

Incidence and molecular underpinnings of donor-cell derived neoplasm among spanish transplantation centers [PDF]

María Gabarrós-Subirà, Sara Torres‐Esquius, Helena Pomares, Francisco Beas, Julia Suárez‐González, Alberto Hernández‐Sánchez, Elisa López‐Fernández, Guillermo Ramil López, María Hermosín-Ramos, Gonzalo Carreño‐Tarragona, Ivan Martín Castillo, Julián García Labrador, Marta Santiago, M. Pascual, Marina Díaz‐Beyá, Guiomar Bautista Carrascosa, Raúl Teruel Montoya, Francisco José Ortuño, Susana Vives, Lucía Garcia Mañó, María Teresa Gómez‐Casares, Ana Alfonso Piérola, Miguel Piris‐Villaespesa, Nuria Revilla, Sara Alonso, Ana Gallego Iborra, Blanca Ferrer Lores, Ramón Díaz‐Uriarte, José Cervera, Lucía López‐Corral, Marta Pratcorona Canela, Ismael Buño, María Julia Montoro, Francisca Hernández, Francesc Bosch Albareda, Montserrat Arnán, David Valcárcel, Carolina Martínez‐Laperche, Andrés Jerez   +38 more
openalex   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Relapsing Blastic Plasmacytoid Dendritic Cell Neoplasm With Neurologic Involvement. [PDF]

Cureus
Rahman Z, Haley A, Gandhi S, Mohamed A, Parza K, Quan JR.   +5 more
europepmc   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

A novel fusion gene of NUP98::CYP2F2P in myeloid neoplasm. [PDF]

Ann Hematol
Huang W, Zhang F, Xie J, Wu C, Wang Q, Wang L, Wang Q, Chen S.   +7 more
europepmc   +1 more source

Disease progression of side-branch intraductal papillary mucinous neoplasms following solid organ transplant

Chase J. Wehrle, Mir Shanaz Hossain, Jenny H. Chang, Breanna Perlmutter, Abby R Gross, Robert Naples, Jamak Modaresi Esfeh, Samer A. Naffouje, Daniel Joyce, R. Simon, Andrea Schlegel, Charles Miller, Koji Hashimoto, Toms Augustin, R. Matthew Walsh   +14 more
openalex   +1 more source

A Microbiota‐ and IL‐15‐Dependent Innate‐Like B Cell Progenitor Expressing E4BP4

Advanced Science, EarlyView.
This work identifies CD3.NKp46.CD19.NK1.1. NK‐B cells enriched in PDK1‐deficient yet present in wild‐type bone marrow. IL‐15 (via CD122) and TLR9‐microbiota signaling maintain their E4BP4 expression. These cells demonstrate innate immunity, preferentially differentiate into B cells, and unveil a novel microbiota‐ and IL‐15‐dependent regulatory pathway ...
Junming He, Xinlei Hou, Xiaomei Feng, Yayun Dong, Mengqi Ren, Surong Deng, Xinru Yang, Donglin Chen, Lingna Zhao, Shasha Chen, Meixiang Yang, Zhongjun Dong   +11 more
wiley   +1 more source