Results 251 to 260 of about 76,990 (339)

A Step-wise, Deterministic and Fatal Mouse Model of Myeloid Neoplasm with Spontaneous Acquisition of Patient-relevant RTK–RAS Mutations

Zarocsinceva MA, Qureshi M, Wilson NK, Giotopoulos G, Sturgess KHM, Vijayabaskar MS, Kinston SJ, Asby R, Adams DJ, Huntly BJ, Calero-Nieto FJ, Gottgens B.   +11 more
europepmc   +1 more source

Prognostic factors of survival in second allogeneic hematopoietic transplantation. [PDF]

Ann Hematol
Cantera Estefanía R, García Ruiz R, Fernández-Luis S, Domínguez-García JJ, Fernández Barge T, Salmanton-García J, Francés Alexandre I, Tobalina García A, Gea Peña A, Gorostidi Álvarez I, Oviedo Madrid M, Bannatyne Undabeitia J, Vega Suárez LP, Terán Díaz M, Sánchez Escamilla M, Colorado Araujo M, López Duarte M, Yáñez San Segundo L, Ocio EM, Bermúdez Rodríguez A.   +19 more
europepmc   +1 more source

Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis

Advanced Science, EarlyView.
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo, Yan Wang, Qiudi Liu, Zhaoyang Luo, Xiaomu Tian, Yuquan Wang, Yang Liu, Zhiwei Ning, Yingying Guo, Huiying Gao, Xinyue Wang, Jinglong Feng, Mengmeng Liu, Dina Saifullina, Yixin Zhang, Tengfei Pan, Yu Bian, Tao Ban, Tianyu Li, Yunyan Gu, Haihai Liang   +20 more
wiley   +1 more source

Immune Checkpoint Inhibitors in Kidney Transplant Recipients: A French Multicenter Retrospective Cohort Study. [PDF]

Transplant Direct
Legris T, Sallée M, Charmetant X, Thaunat O, Matignon M, Joher N, Pernin V, Sicard A, Kaminski H, Couzi L, Moal V.   +10 more
europepmc   +1 more source

Proceedings: The effect of immunosuppression on cancer. [PDF]

, 1972
Penn, I, Starzl, TE
core  

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

Advanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma   +17 more
wiley   +1 more source

Case Report: Rapid response to gemtuzumab-ozogamicin in a pediatric patient with refractory systemic mastocytosis with AML1::ETO+ acute myeloid leukemia. [PDF]

Front Immunol
Xue S, Chen M, Sun HP, Wang T, Zhang LN, Cao XY.   +5 more
europepmc   +1 more source

Control of post-transplant lymphoproliferative disorders and Kaposi's sarcoma by modulation of immunosuppression [PDF]

, 1987
Breinig, MK, Demetris, AJ, Griffith, BP, Ho, M, Iwatsuki, S, Jaffe, R, Makowka, L, Nalesnik, M, Starzl, TE, Steiber, A, Tzakis, A   +10 more
core  

A Complementarity‐Based Approach to De Novo Binder Design

Advanced Science, EarlyView.
A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko, Valeriia Hatskovska, Murray Coles, Narges Aghaallaei, Natalia Pashkovskaia, Natalia Borbarán‐Bravo, Matteo Pilz, Philip Bucher, Mareike Volz, Joana Pereira, Marcus D. Hartmann, Ghazaleh Tabatabai, Judith Feucht, Stefan Liebau, Patrick Müller, Andrei N. Lupas, Julia Skokowa, Mohammad ElGamacy   +17 more
wiley   +1 more source

Long-Term Outcomes After Kidney Transplantation in a Recipient With Birt-Hogg-Dubé Syndrome. [PDF]

Case Rep Transplant
Abraham ASM, Medina A, Esmail R, Trestrail T, Rivera FC.   +4 more
europepmc   +1 more source