Results 251 to 260 of about 163,967 (338)

Allogeneic Hematopoietic Cell Transplantation (HCT) Outcomes in Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN)

open access: hybrid, 2014
Betty K. Hamilton   +10 more
openalex   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

open access: yesAdvanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan   +19 more
wiley   +1 more source

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

open access: yesAdvanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu   +10 more
wiley   +1 more source

Leveraging machine learning to predict de novo skin malignancy following lung transplantation. [PDF]

open access: yesLung Cancer Manag
Nosoudi N   +4 more
europepmc   +1 more source

Bone marrow transplantation reduces FGF-23 levels and restores bone formation in myelodysplastic neoplasms [PDF]

open access: hybrid
Heike Weidner   +10 more
openalex   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

open access: yesAdvanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian   +5 more
wiley   +1 more source

Impact of Hereditary Cancer Susceptibility in Solid-Organ Transplant Recipients. [PDF]

open access: yesJCO Precis Oncol
Khuu N   +9 more
europepmc   +1 more source

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