Results 261 to 270 of about 163,967 (338)

Liver Transplant Patients Have a Risk of Progression Similar To That of Sporadic Patients With Branch Duct Intraductal Papillary Mucinous Neoplasms

, 2014
Anne Marie Lennon, David I. Victor, Atif Zaheer, Mohammad R. Ostovaneh, Jessica Jeh, Joanna K. Law, Neda Rezaee, Marco Dal Molin, Young Joon Ahn, Wenchuan Wu, Mouen A. Khashab, Mohit Girotra, Nita Ahuja, Martin A. Makary, Matthew J. Weiss, Kenzo Hirose, Michael Goggins, Ralph H. Hruban, Andrew M. Cameron, Christopher L. Wolfgang, Vikesh K. Singh, Ahmet Gürakar   +21 more
openalex   +2 more sources

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Driver mutation-defined molecular landscapes of essential thrombocythemia. [PDF]

Blood Sci
Lorenzen AL, Huang G.
europepmc   +1 more source

REMOVED: Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Mature NK/T Cell Neoplasms – Potent Graft Vs Tumor Effect Affords Remission Even with Refractory Disease

Kamil Rechache, Jennifer Sponaugle, Amy Chai, Jessenia Campos, Thomas E. Hughes, Syed Muhammad Salman Shah, Andrea Peluso, Christi McKeown, Anita Stokes, Scott Napier, Ruby Sabina, Jennifer Wilder, Kristen Cole, Mustafa Hyder, Christopher G. Kanakry, Dimana Dimitrova, Jennifer A. Kanakry   +16 more
openalex   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

ON THE OCCURRENCE OF MUTATIONS WITHIN TRANSPLANTABLE NEOPLASMS [PDF]

Genetics, 1926
openaire   +2 more sources

A Proposal for Expedited Stem Cell Transplantation for TP53-Mutant Myelodysplastic Neoplasms and Acute Myeloid Leukemia [PDF]

Shyam A. Patel, Steven M. Devine, Jan Cerny   +2 more
openalex   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

Advanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao, Qian Hao, Yu Gan, Jing Tong, Xiaodan Chen, Shuran Tan, Ruiwen Ruan, Yingdan Huang, Mingming Cao, Jun Deng, Tao Han, Getao Shi, Bo Gao, Yu Zhang, Xiang Zhou   +14 more
wiley   +1 more source

Allogeneic haematopoietic cell transplantation in advanced systemic mastocytosis in the new era: A CIBMTR study. [PDF]

Br J Haematol
Ustun C, Zhang MJ, Peterson A, Baek A, Agha M, Alkhateeb H, Chhabra S, Coltoff A, de Lima M, Gandhi A, Ho V, Kassim A, Lin A, Gowda L, Borthakur G, DeAngelo DJ, McGuirk J, Mensah F, Nadiminti KV, Nishihori T, Pantin J, Trunk A, Uberti J, Marcucci G, Gotlib J, Akin C, Hamadani M, Pullarkat V, Valent P, Grunwald M, Juckett M, Oran B, Saber W, Burns LJ.   +33 more
europepmc   +1 more source

PEDOT:PSS—A Key Material for Bioelectronics

Advanced Science, EarlyView.
PEDOT:PSS ‐ Poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate ‐ is typically processed from water dispersions to form multifunctional and multidimensional constructs with tunable electronic and ionic conductivity. Throught processing engineering, PEDOT:PSS is intergrated in bioelectronic devices that operate efficiently in physiological conditions
Alan Eduardo Ávila Ramírez, David Pieter van der Laan, Mustafeez Bashir Shah, Liwen Wang, Erica Zeglio, Achilleas Savva   +5 more
wiley   +1 more source