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The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.

open access: yesBlood, 2016
The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues was last updated in 2008. Since then, there have been numerous advances in the identification of unique biomarkers associated with some myeloid ...
D. Arber   +8 more
semanticscholar   +1 more source

Oxaliplatin plus S-1 with intraperitoneal paclitaxel for the treatment of Chinese advanced gastric cancer with peritoneal metastases

open access: yesBMC Cancer, 2021
Background In this study, we tried to access the efficacy and safety of oxaliplatin plus S-1 with intraperitoneal paclitaxel (PTX) for the treatment of Chinese advanced gastric cancer with peritoneal metastases.
Min Shi   +18 more
doaj   +1 more source

The consequences of cohesin mutations in myeloid malignancies

open access: yesFrontiers in Molecular Biosciences, 2023
Recurrent somatic mutations in the genes encoding the chromatin-regulatory cohesin complex and its modulators occur in a wide range of human malignancies including a high frequency in myeloid neoplasms. The cohesin complex has a ring-like structure which
Shubhra Ashish Bhattacharya   +6 more
doaj   +1 more source

Cross-Database Analysis Reveals Sensitive Biomarkers for Combined Therapy for ERBB2+ Gastric Cancer

open access: yesFrontiers in Pharmacology, 2018
Exploring ERBB2-related pathways will help us finding sensitive molecules and potential combined therapeutic targets of ERBB2-targeted therapy for ERBB2+ gastric cancer (GC). In this study, we performed a cross-databases study focused on ERBB2+ GC.
Zhen Xiang   +8 more
doaj   +1 more source

Immune Thrombocytopenia and JAK2V617F Positive Essential Thrombocythemia: Literature Review and Case Report

open access: yesCase Reports in Hematology, 2017
We present the case where immune thrombocytopenia (ITP) and essential thrombocythemia (ET) sequentially appeared in the space of twenty-one years of follow-up.
M. A. Sobas   +8 more
doaj   +1 more source

A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background IDO1 (Indoleamine 2,3-dioxygenase 1) inhibits host anti-tumor immune response by exhausting tryptophan in tumor microenvironment, but the pathogenic mechanisms of IDO1 in gastric cancer (GC) cells need to be further explored.
Zhen Xiang   +10 more
doaj   +1 more source

Study protocol of a multicenter phase III randomized controlled trial investigating the efficiency of the combination of neoadjuvant chemotherapy (NAC) and neoadjuvant laparoscopic intraperitoneal hyperthermic chemotherapy (NLHIPEC) followed by R0 gastrectomy with intraoperative HIPEC for advanced gastric cancer (AGC): dragon II trial

open access: yesBMC Cancer, 2020
Background Even though treatment modalities such as adjuvant systemic radio-chemotherapy and neoadjuvant chemotherapy (NAC) have individually have improved overall survival (OS) and progression-free survival (PFS) rates in advanced Gastric Cancer (AGC ...
Maneesh Kumarsing Beeharry   +10 more
doaj   +1 more source

A case report of pediatric acute lymphoblastic leukemia with e8a2 BCR/ABL1 fusion transcript

open access: yesBMC Medical Genomics, 2022
Background Acute lymphoblastic leukemia is the most common type of cancer in children. Most often it affects the age group between 2 and 5 years of age. Studies have shown an improvement in general survivability, more than 90% 5-year overall survival (OS)
Aleksandra Mroczkowska   +8 more
doaj   +1 more source

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes.

open access: yesBlood, 2009
Recently the World Health Organization (WHO), in collaboration with the European Association for Haematopathology and the Society for Hematopathology, published a revised and updated edition of the WHO Classification of Tumors of the Hematopoietic and ...
J. Vardiman   +10 more
semanticscholar   +1 more source

The 2016 revision of the World Health Organization classification of lymphoid neoplasms.

open access: yesBlood, 2016
A revision of the nearly 8-year-old World Health Organization classification of the lymphoid neoplasms and the accompanying monograph is being published. It reflects a consensus among hematopathologists, geneticists, and clinicians regarding both updates
S. Swerdlow   +10 more
semanticscholar   +1 more source

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