Results 61 to 70 of about 2,063,706 (306)

Desmoplastic melanoma: a rare variant with challenging diagnosis [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2019
: Desmoplastic melanoma, a distinct and uncommon variant, is characterized as an invasive lesion with proliferation of fusiform melanocytes in the dermis and subcutaneous tissue, associated with varying patterns of desmoplasia.
Priscila Castelan Marques   +3 more
doaj   +1 more source

Molecular changes in solitary fibrous tumor progression

open access: yesJournal of molecular medicine, 2019
Solitary fibrous tumors (SFTs) are NAB2-STAT6 fusion-associated neoplasms. There are several subtypes of NAB2-STAT6 fusions, but their clinical significances are still unclear. Moreover, the mechanisms of malignant progression are also poorly understood.
H. Park   +13 more
semanticscholar   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Craniofacial fibrous dysplasia: Report of a case using computed tomographic scan diagnosis

open access: yesJournal of Orofacial Sciences, 2013
Fibro-osseous lesions are benign mesenchymal tumors in which mineralized tissue, blood vessels, and giant cells, in varying proportions, replace normal bone. Although this group of lesions includes reactive lesions, harmatomas, and neoplasms, they cannot
Nikhil Diwan   +3 more
doaj   +1 more source

Intracranial Myxoid Mesenchymal Tumor/Myxoid Subtype Angiomatous Fibrous Histiocytoma: Diagnostic and Prognostic Challenges.

open access: yesNeurosurgery, 2020
BACKGROUND AND IMPORTANCE In the setting of intracranial neoplasms, EWSR1-cAMP Response Element-Binding Protein (CREB) transcription factor family fusions have been described in myxoid mesenchymal tumors, extremely rare entities with a close ...
R. Domingo   +3 more
semanticscholar   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Giant Solitary Fibrous Tumor of the Pleura in Two Cases

open access: yesEurasian Journal of Medicine, 2019
Solitary fibrous tumors of the pleura are rare neoplasms and account for less than 5% of all pleural tumors. They originate from mesenchimal cells of the submesothelial tissue of the pleura. They present as a discrete, pediculated and encapsulated tumor.
Atila Türkyılmaz   +3 more
doaj  

PATHOLOGICAL STUDIES ON LIVER AND BILE DUCT TUMORS IN SUDANESE CATTLE [PDF]

open access: yesAssiut Veterinary Medical Journal
Due to their rare occurrence in bovine species, neoplasms of the liver and bile ducts were reported in few available researches. In Egypt, their prevalence in domestic animals was documented in a few records. An abattoir-based survey was conducted at Abu-
MOHAMED YOUSSEF   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Myxofibrosarcoma: a diagnostic pitfall

open access: yesRare Tumors, 2013
Myxofibrosarcoma (MFS) is a variant of the group of malignant fibrous histiocytomas. It is one of the most aggressive types of soft tissue neoplasms.
Charlotte Castronovo   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy