Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
Abdominal Wall Desmoid Tumor Misdiagnosed as Schwannoma: A Case Report. [PDF]
Limaiem F, Hajri M.
europepmc +1 more source
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che +9 more
wiley +1 more source
Dorsal midline ectopic mammary tissue as a cutaneous marker of spinal dysraphism: intradural lipoma and tethered cord in a child with literature review. [PDF]
Alcazar P +8 more
europepmc +1 more source
This work develops a breathable potentiometric self‐powered pressure sensor with good wearability, using a non‐woven fabric substrate and hydrogel electrolyte. The sensor is integrated into a five‐channel smart glove to acquire reliable hand motion signals, which are processed by a CNN for identity verification and smart vehicle control in human ...
Qilong Zhang +10 more
wiley +1 more source
Assessment of intratumoral collagen in pituitary neuroendocrine tumors (pituitary adenomas/PitNets) via digital pathology and its correlation with intraoperative consistency. [PDF]
A AC +7 more
europepmc +1 more source
Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang +13 more
wiley +1 more source
Mesenteric desmoid tumor with diagnostic challenge mimicking a malignant small intestinal tumor: a case report. [PDF]
Tokumaru T +5 more
europepmc +1 more source
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang +15 more
wiley +1 more source
Epithelioid fibrous histiocytoma of eyelid in children: A case report. [PDF]
Sun Z +6 more
europepmc +1 more source

