Results 41 to 50 of about 240,307 (274)
Immunohistochemical diagnosis of primary cardiac leiomyosarcoma in a Latin American patient
Rare Tumors, 2017 Primary cardiac malignancies are rare entities. Although sarcomas enclosed the main group of malignant heart neoplasms, primary cardiac leiomyosarcomas are extremely rare and constitutes less than 8% of cardiac tumors.
Ruben Blachman-Braun +6 more
doaj +1 more source
The expression of CD90/Thy-1 in hepatocellular carcinoma: an in vivo and in vitro study. [PDF]
PLoS ONE, 2013 Although the CD90 (Thy-1) was proposed as biomarker of several tumors and cancer stem cells, the involvement of this molecule in the progression of hepatocellular carcinoma (HCC) and other less frequent hepatic neoplasms is still undefined.
Caecilia Hapsari Ceriapuri Sukowati +5 more
doaj +1 more source
Features of molecular mechanisms of insulin resistance pathogenesis in various tissues in obesity
Ожирение и метаболизм, 2023 Obesity is a chronic pathology, which experts of theWorld Health Organization regard as an epidemic, based on the high rates of annual growth in the proportion of the overweight population in almost all countries of the world.
D. I. Kuzmenko +4 more
doaj +1 more source
Intramuscular (infiltrating) Lipoma [PDF]
, 2011 Intraoral lipomas are benign and relatively rare tumors, although they occur with higher frequencies in other areas, most especially the back, abdomen and shoulders of adults.
Kashyap, Bina +2 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Neuronavigational approach for orbital neurofibroma excision: a case report [PDF]
, 2015 Orbital neurofibromas are uncommon in adults, accounting for approximately 1%-3% of all space occupying lesions of the orbit. The complex anatomy of the orbital region, with the pronounced vulnerability of its neurovascular structures, requires ...
CASCONE, PIERO +5 more
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Open Veterinary JournalBackground: This report describes a case of uterine leiomyoma and cystic endometrial hyperplasia in an Asian elephant (Elephas maximus). Case Description: A 74-year-old female elephant in captivity was necropsied.
Gustavo Willian Pandolfo +7 more
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]
, 2015 Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David +8 more
core +3 more sources