Results 101 to 110 of about 319,310 (259)

Assessing the rigidity of thermoplastic masks for head immobilization effectiveness in stereotactic radiosurgery

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract This study compared three Brainlab thermoplastic masks—Cranial 4pi basic, stereotactic (Close Mask V2), and open‐face—to see how well they limited head movement during Stereotactic Radiosurgery (SRS). Using a head phantom, we tested rotational movements (pitch, yaw, and roll) and measured displacements with the ExacTrac system.
Iris Pasion Apale, Adam Agnew, Daniel Foley   +2 more
wiley   +1 more source

Dosimetric effect of silicone‐based gel on skin surface during volumetric modulated arc therapy for breast cancer

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to quantify and compare the dosimetric effects of varying thicknesses of StrataXRT, a silicone‐based gel, and other topical agents on the skin surface during volumetric modulated arc therapy (VMAT) for breast cancer.
Tenyoh Suzuki, Shingo Ohira, Mami Ogita, Takeshi Ohta, Yuki Nozawa, Masanari Minamitani, Takuya Hayashi, Shigeki Saegusa, Toshikazu Imae, Tsuyoshi Ueyama, Atsuto Katano, Hideomi Yamashita, Weishan Chang, Keiichi Nakagawa   +13 more
wiley   +1 more source

Comprehensive clinical evaluation of novel 4DCT‐based lung function imaging methods

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Methods have been developed that apply image processing to 4DCTs to generate 4DCT‐ventilation/perfusion lung imaging. Traditional methods for 4DCT‐ventilation rely on Hounsfield‐Unit (HU) density‐change methods and suffer from poor numerical robustness while not providing 4DCT‐perfusion data.
Ehsan Golkar, Taindra Neupane, Lydia Wilson, Jennifer Kwak, Richard Castillo, Edward Castillo, Yevgeniy Vinogradskiy   +6 more
wiley   +1 more source

Log file‐based quality assurance method for respiratory gating system

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background As medical linear accelerator technology advances, enabling higher dose rate deliveries, hypofractionation regimens has increased. This necessitates respiratory gating systems that synchronize radiation delivery with tumor position, requiring simple rigorous quality assurance (QA) to ensure treatment accuracy and patient safety ...
Wonjoong Cheon, Young Kyu Lee, Yunji Seol, Chan‐beom Park, Hong Qi Tan, Kyu Hye Choi, Young‐nam Kang, Byung Ock Choi   +7 more
wiley   +1 more source

Machine stability and dosimetry for ultra‐high dose rate FLASH radiotherapy human clinical protocol

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The FLASH effect, induced by ultra‐high dose rate (UHDR) irradiations, offers the potential to spare normal tissue while effectively treating tumors. It is important to achieve precise and accurate dose delivery and to establish reliable detector systems, particularly for clinical trials needed to help the clinical transfer of FLASH‐
Patrik Gonçalves Jorge, Reiner Geyer, Rémy Kinj, Luis Schiappacasse, Wendy Jeanneret‐Sozzi, Jean Bourhis, Fernanda Herrera, François Bochud, Claude Bailat, Raphaël Moeckli   +9 more
wiley   +1 more source

An investigation into the feasibility and efficacy of stereotactic radiosurgery for 1–3 cm single brain lesions on the ring‐mounted Halcyon LINAC

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose An evaluation of the accuracy, safety, and efficiency of the Halcyon ring delivery system (RDS) for stereotactic radiosurgery (SRS) treatment to relatively small (1–3 cm) brain lesions. Methods After completing the extensive in‐house quality assurance checks including Winston–Lutz test and independent dose verification via MD Anderson ...
Kate Hazelwood, Shane McCarthy, Josh Misa, David Castelvetere, William St. Clair, Damodar Pokhrel   +5 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

A General Cyanine‐Based Platform for Designing Robust Dual‐Channel Near‐Infrared Fluorescent and Photoacoustic Probes

Advanced Functional Materials, EarlyView.
The study presents a general cyanine‐based platform CySN for designing robust dual‐channel near‐infrared fluorescent (NIRF) and photoacoustic (PA) probes with high ratiometric signals change. CySN enables the construction of highly sensitive and selective dual‐channel NIRF/PA probes for both small molecule and enzyme biomarkers (H2O2, esterase ...
Pingzhou Wu, Zheng Qu, Jie Zhang, Xiaojie Ren, Dongqing Wang, Chen Huang, Ke Cheng, Junyang Qi, Heng Shi, Shenglong Gan, Wenyu Wei, Yachao Zhang, Chun‐Sing Lee, Lidai Wang, Hongyan Sun   +14 more
wiley   +1 more source

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

Advanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng, Shan Xu, Yi Lei, Huizhou He, Runbin Sun, Xingle Jin, Cheneryu Huang, Yuhao Zheng, Jianqing Peng, Lei Tang, Peng Luo, Yi Chen, Shuai Zhang   +12 more
wiley   +1 more source