Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]
, 2018 The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski +11 more
core +1 more source
Radiation exposure by medical X-ray applications
GMS German Medical Science, 2022 Background: Radioactive material and ionising radiation play a central role in medical diagnostics and therapy. The benefit of ionising radiation is opposed by the risk of irreparable damage of the human organism.
Buchberger, Barbara +4 more
doaj +1 more source
Spontaneous and Radiation-Induced Chromosome Aberrations in Primary Fibroblasts of Patients With Pediatric First and Second Neoplasms [PDF]
Frontiers in Oncology, 2020 The purpose of the present study was to investigate whether former childhood cancer patients who developed a subsequent secondary primary neoplasm (SPN) are characterized by elevated spontaneous chromosomal instability or cellular and chromosomal radiation sensitivity as surrogate markers of compromised DNA repair compared to childhood cancer patients ...
Zahnreich, Sebastian +12 more
openaire +5 more sources
Journal of Investigative Medicine High Impact Case Reports, 2013 Background: It is recognized that various radiation-induced malignancies often follow childhood radiotherapy. Radiation-induced neoplasms have been shown to occur with increased frequency in syndromes due to mutated tumor suppressor genes. There exist no
Patrick A. Williams BS +4 more
doaj +1 more source
Intranasal melanoma treated with radiation therapy in three dogs [PDF]
, 2017 Three dogs were investigated for chronic unilateral nasal discharge. In all cases CT imaging showed an intranasal mass causing turbinate lysis and no evidence of metastasis.
Blackwood, L +6 more
core +4 more sources
The current diagnosis of superficial bladder cancer must be reconsidered [PDF]
, 2002 The high recurrence and progression rates in superficial bladder cancer are partially related to the deficiencies of the standard conventional diagnostic modalities.
Hofstetter, Alfons, Zaak, Dirk
core +1 more source
Salvage resection of advanced mediastinal tumors [PDF]
, 2019 The surgical treatment of locally advanced mediastinal tumors invading the great vessels and other nearby structures still represent a tricky question, principally due to the technical complexity of the resective phase, the contingent need to carry out
Andreetti, Claudio +9 more
core +1 more source
Genetic Pathway in the Pathogenesis of Therapy-Related Myeloid Neoplasms: A Literature Review
Oncology and Therapy, 2020 Therapy-related myeloid neoplasms are a life-threatening and often fatal complication, associated with poor prognosis outcomes and with high-risk unfavorable cytogenetic abnormalities including complex karyotype. They occur after the treatment of primary
Tegenaw Tiruneh +2 more
doaj +1 more source
Radiogenic Vaginal Angiosarcoma: a Clinical Case
Креативная хирургия и онкология, 2020 Background. Vaginal sarcomas are rare malignant mesenchymal neoplasms. Incidence rate of vulvar and vaginal sarcomas ranges from 1 to 3%. Vaginal sarcomas are usually represented by leiomyosarcomas in reproductive-age women.
K. V. Menshikov +4 more
doaj +1 more source
Local treatment with electrochemotherapy of superficial angiosarcomas: Efficacy and safety results from a multi-institutional retrospective study [PDF]
, 2016 Background: Angiosarcoma is an aggressive vascular neoplasm with a high propensity for local recurrence. Electrochemotherapy is an emerging skin-directed therapy, exerting prominent cytotoxic activity, and antivascular effects.
Bonadies, CARLO ALBERTO +12 more
core +1 more source