Results 61 to 70 of about 200,124 (304)

Assessing radiation-induced carotid vasculopathy using ultrasound after unilateral irradiation: a cross-sectional study

Radiation Oncology, 2022
Background Increased head and neck cancer (HNC) survival requires attention to long-term treatment sequelae. Irradiated HNC survivors have a higher ischemic stroke risk. However, the pathophysiology of radiation-induced vasculopathy is unclear.
Judith T. Pruijssen, Joyce Wilbers, Frederick J. A. Meijer, Sjoert A. H. Pegge, Jacqueline J. Loonen, Chris L. de Korte, Johannes H. A. M. Kaanders, Hendrik H. G. Hansen   +7 more
doaj   +1 more source

Intramedullary Glioblastoma as One of Multiple Radiation-Induced Neoplasms

Case Reports in Oncology
Introduction: Intramedullary glioblastoma is a rare entity comprising 1.4–9% of spinal gliomas. Spinal cord radiation-induced gliomas are unique, with only 13 cases reported to date. Case Presentation: A 53-year-old female with a history of mediastinal Hodgkin lymphoma treated with chemotherapy and radiotherapy who subsequently developed thyroid cancer
Koczyk, Kacper, Nowak, Arkadiusz, Machnicki, Marcin M., Michałowski, Łukasz Zdzisław, Maj, Edyta, Stoklosa, Tomasz, Kunert, Przemysław   +6 more
openaire   +2 more sources

Early induction and increased risk of precursor B-cell neoplasms after exposure of infant or young-adult mice to ionizing radiation

, 2020
Epidemiological studies of atomic-bomb survivors have revealed an increased risk of lymphoid neoplasm (i.e. acute lymphoblastic leukemia) associated with radiation exposure.
943341, 943342, 943343, 943344, 943345, 943346, Shimada, Yoshiya, 943347, 943348, Tachibana, Hirotaka, 943340, Daino, Kazuhiro, Matsuura, Akira, Shizuko, Kakinuma, Yoshiya, Shimada, 943338, 943339, Kazuhiro, Daino, Hirotaka, Tachibana, Mari, Ogawa, Fujita, Misuzu, Kakinuma, Shizuko, Ogawa, Mari, 943334, 943335, 943336, 943337, 943350, Shang, Yi, Yi, Shang, Misuzu, Fujita, Morioka, Takamitsu, Takamitsu, Morioka, 943349   +33 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Radiation Therapy for Solitary Plasmacytoma and Multiple Myeloma: Guidelines From the International Lymphoma Radiation Oncology Group

, 2018
PURPOSE: To develop guidelines for the work-up and radiation therapy (RT) management of patients with plasma cell neoplasms. METHODS AND MATERIALS: A literature review was conducted covering staging, work-up, and RT management of plasma cell neoplasms ...
서창옥
core   +1 more source

Modeling DNA damage-induced pneumopathy in mice: insight from danger signaling cascades

Radiation Oncology, 2017
Radiation-induced pneumonitis and fibrosis represent severe and dose-limiting side effects in the radiotherapy of thorax-associated neoplasms leading to decreased quality of life or - as a consequence of treatment with suboptimal radiation doses - to ...
Florian Wirsdörfer, Verena Jendrossek
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Low-Dose Gamma-Radiation Inhibits Benzo[a]pyrene-Induced Lung Adenoma Development in A/J Mice

Dose-Response, 2012
Low-dose ionizing radiation (LDR) may lead to suppression of smoking-related lung cancer. We examined the effects of a known cigarette smoke carcinogen Benzo[a]pyrene (B[a]P) alone or in combination with fractionated low-dose gamma radiation (60 – 600 ...
Veronica R. Bruce, Steven A. Belinsky, Katherine Gott, Yushi Liu, Thomas March, Bobby Scott, Julie Wilder   +6 more
doaj   +1 more source

Imaging Methods for Pancreatic Neoplasms

, 2022
Imaging of pancreatic neoplasms is complex and insidious, requiring a deep knowledge of radiological techniques but also a very thorough knowledge of pancreatic pathology, its management, its risk factors, and possible complications.
Calbi, Roberto, D'Onofrio, Mirko, Cominziolli, Annalisa, Longo, Chiara, De Robertis, Riccardo, Cardobi, Nicolò, Urraro, Fabrizio, Beleù, Alessandro   +7 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source