Results 131 to 140 of about 2,036,299 (361)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Fine needle aspiration of thyroid nodules in a general teaching hospital setting performing moderate number of biopsies: Outcome of indeterminate cytologic results [PDF]
Introduction: Our aim was to assess the usefulness of fine-needle aspiration cytologic biopsy (FNA) of the thyroid in our general teaching hospital with average health care facility performing moderate number of such procedures and to evaluate the ...
Azarhoush, R. +2 more
core
Comparative histopathology of gonadal neoplasms in marine bivalve mollusks
Esther C. Peters +3 more
openalex +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Significance of GRP78 expression in acute myeloid leukemias
Wróbel Tomasz +7 more
doaj +1 more source
Ascites in the Course of Plasma Cell Myeloma Complicated by AL Amyloidosis
Jakub Debski +5 more
doaj +1 more source

