Results 11 to 20 of about 2,263,454 (404)

The dynamic alteration of transcriptional regulation by crucial TFs during tumorigenesis of gastric cancer

open access: yesMolecular Medicine, 2022
Background The mechanisms of Gastric cancer (GC) initiation and progression are complicated, at least partly owing to the dynamic changes of gene regulation during carcinogenesis. Thus, investigations on the changes in regulatory networks can improve the
Beiqin Yu   +13 more
doaj   +1 more source

Prediction Model of Tumor Regression Grade for Advanced Gastric Cancer After Preoperative Chemotherapy

open access: yesFrontiers in Oncology, 2021
BackgroundPreoperative chemotherapy (PCT) has been considered an important treatment for advanced gastric cancer (AGC). The tumor regression grade (TRG) system is an effective tool for the assessment of patient responses to PCT.
Wei Xu   +17 more
doaj   +1 more source

LncRNA MALAT1 promotes gastric cancer progression via inhibiting autophagic flux and inducing fibroblast activation

open access: yesCell Death and Disease, 2021
Autophagy defection contributes to inflammation dysregulation, which plays an important role in gastric cancer (GC) progression. Various studies have demonstrated that long noncoding RNA could function as novel regulators of autophagy.
Zhenqiang Wang   +6 more
doaj   +1 more source

Oxaliplatin plus S-1 with intraperitoneal paclitaxel for the treatment of Chinese advanced gastric cancer with peritoneal metastases

open access: yesBMC Cancer, 2021
Background In this study, we tried to access the efficacy and safety of oxaliplatin plus S-1 with intraperitoneal paclitaxel (PTX) for the treatment of Chinese advanced gastric cancer with peritoneal metastases.
Min Shi   +18 more
doaj   +1 more source

Sebaceous Neoplasms

open access: yesDiagnostics, 2023
Sebaceous neoplasms describe a group of tumors with sebaceous differentiation commonly seen in lesions located primarily in the face and neck. The majority of these lesions are benign, while malignant neoplasms with sebaceous differentiation are uncommon. Sebaceous tumors present a strong association with the Muir–Torre Syndrome.
Ilias Papadimitriou   +5 more
openaire   +3 more sources

The consequences of cohesin mutations in myeloid malignancies

open access: yesFrontiers in Molecular Biosciences, 2023
Recurrent somatic mutations in the genes encoding the chromatin-regulatory cohesin complex and its modulators occur in a wide range of human malignancies including a high frequency in myeloid neoplasms. The cohesin complex has a ring-like structure which
Shubhra Ashish Bhattacharya   +6 more
doaj   +1 more source

Some considerations on the WHO Histological classification of laryngeal neoplasms [PDF]

open access: yes, 2019
A new edition of the World Health Organization (WHO) Histological classification of tumours of the hypopharynx, larynx, trachea and parapharyngeal space was published in 2017.
Devaney, Kenneth O.   +3 more
core   +2 more sources

Immune Thrombocytopenia and JAK2V617F Positive Essential Thrombocythemia: Literature Review and Case Report

open access: yesCase Reports in Hematology, 2017
We present the case where immune thrombocytopenia (ITP) and essential thrombocythemia (ET) sequentially appeared in the space of twenty-one years of follow-up.
M. A. Sobas   +8 more
doaj   +1 more source

Cross-Database Analysis Reveals Sensitive Biomarkers for Combined Therapy for ERBB2+ Gastric Cancer

open access: yesFrontiers in Pharmacology, 2018
Exploring ERBB2-related pathways will help us finding sensitive molecules and potential combined therapeutic targets of ERBB2-targeted therapy for ERBB2+ gastric cancer (GC). In this study, we performed a cross-databases study focused on ERBB2+ GC.
Zhen Xiang   +8 more
doaj   +1 more source

A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background IDO1 (Indoleamine 2,3-dioxygenase 1) inhibits host anti-tumor immune response by exhausting tryptophan in tumor microenvironment, but the pathogenic mechanisms of IDO1 in gastric cancer (GC) cells need to be further explored.
Zhen Xiang   +10 more
doaj   +1 more source

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