Results 211 to 220 of about 2,036,299 (361)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Second Primary Cancer After Bladder Cancer: A Comprehensive Analysis of a National Cancer Registry. [PDF]

Cancer Med
Buchler T, Pehalova Kusova L, Pirshtuk A, Muzik J, Babjuk M, Dusek L.   +5 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Orthotopic Liver Transplantation for Benign Hepatic Neoplasms [PDF]

, 1995
Iwatsuki, S, Madariaga, JR, Selby, R, Starzl, TE, Tepetes, K, Webb, M   +5 more
core   +1 more source

Global burden and future projections of non-communicable diseases (2000-2050): Progress toward SDG 3.4 and disparities across regions and risk factors. [PDF]

PLoS One
Freihat O, Sipos D, Aamir M, Kovacs A.
europepmc   +1 more source

Aggressive Papillary Tumor of the Middle Ear: A True Entity or an Endolymphatic Sac Neoplasm? [PDF]

, 2008
James R. Tysome, Jonny Harcourt, Manish C. Patel, Ann Sandison, L. Michaels   +4 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Improvement in quality of life of bitches with malignant mammary neoplasms after unilateral mastectomy and regional lymphadenectomy. [PDF]

Braz J Vet Med
Bossi MTDS, Moreno MH, Hadi NIIA, Vicenzi A, de Oliveira CRT, Rodrigues EO, Dos Santos LMS, Gruchowski L, Dalmolin C, Elias F, Dalmolin F.   +10 more
europepmc   +1 more source

TRIM29 as a prognostic predictor for multiple human malignant neoplasms: a systematic review and meta-analysis [PDF]

, 2017
Chao Liang, Huiyu Dong, Chenkui Miao, Jundong Zhu, Jie Wang, Pu Li, Jie Li, Zengjun Wang   +7 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source