Results 21 to 30 of about 2,263,454 (404)

Study protocol of a multicenter phase III randomized controlled trial investigating the efficiency of the combination of neoadjuvant chemotherapy (NAC) and neoadjuvant laparoscopic intraperitoneal hyperthermic chemotherapy (NLHIPEC) followed by R0 gastrectomy with intraoperative HIPEC for advanced gastric cancer (AGC): dragon II trial

open access: yesBMC Cancer, 2020
Background Even though treatment modalities such as adjuvant systemic radio-chemotherapy and neoadjuvant chemotherapy (NAC) have individually have improved overall survival (OS) and progression-free survival (PFS) rates in advanced Gastric Cancer (AGC ...
Maneesh Kumarsing Beeharry   +10 more
doaj   +1 more source

Tumor suppressor lnc-CTSLP4 inhibits EMT and metastasis of gastric cancer by attenuating HNRNPAB-dependent Snail transcription

open access: yesMolecular Therapy: Nucleic Acids, 2021
Tumor metastasis is a crucial impediment to the treatment of gastric cancer (GC), and the epithelial-to-mesenchymal transition (EMT) program plays a critical role for the initiation of GC metastasis.
Tao Pan   +15 more
doaj   +1 more source

Cancer-associated fibroblasts impair the cytotoxic function of NK cells in gastric cancer by inducing ferroptosis via iron regulation

open access: yesRedox Biology, 2023
As the predominant immunosuppressive component within the tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) inhibit Natural Killer cell (NK cell) activity to promote tumor progression and immune escape; however, the mechanisms of cross ...
Lizhong Yao   +14 more
doaj   +1 more source

Retrospective study of more than 9000 feline cutaneous tumours in the UK: 2006–2013 [PDF]

open access: yes, 2017
The aim of the study was to utilise a large database available from a UK-based, commercial veterinary diagnostic laboratory to ascertain the prevalence of different forms of cutaneous neoplasia within the feline population, and to detect any breed, sex ...
Dobromylskyj, M J, Ho, N T, Smith, K C
core   +1 more source

A case report of pediatric acute lymphoblastic leukemia with e8a2 BCR/ABL1 fusion transcript

open access: yesBMC Medical Genomics, 2022
Background Acute lymphoblastic leukemia is the most common type of cancer in children. Most often it affects the age group between 2 and 5 years of age. Studies have shown an improvement in general survivability, more than 90% 5-year overall survival (OS)
Aleksandra Mroczkowska   +8 more
doaj   +1 more source

Clinical reasoning in canine spinal disease: what combination of clinical information is useful? [PDF]

open access: yes, 2015
Spinal disease in dogs is commonly encountered in veterinary practice. Numerous diseases may cause similar clinical signs and presenting histories. The study objective was to use statistical models to identify combinations of discrete parameters from the
ABRAMSON   +36 more
core   +2 more sources

Radon and Neoplasms

open access: yesToxics, 2023
Radon is a carcinogenic factor, but the effects of the potential carcinogenicity of radon progeny on the human body during the prenatal period have not yet been explored. Based on data regarding the half-lives of radon-222 and radon-220 and their progeny, this paper considers their potential effects on the human body in the prenatal period.
openaire   +3 more sources

A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal

open access: yesModern Pathology, 2018
The classification of neuroendocrine neoplasms (NENs) differs between organ systems and currently causes considerable confusion. A uniform classification framework for NENs at any anatomical location may reduce inconsistencies and contradictions among ...
G. Rindi   +25 more
semanticscholar   +1 more source

DKK1 as a robust predictor for adjuvant platinum chemotherapy benefit in resectable pStage II-III gastric cancer

open access: yesTranslational Oncology, 2023
Background: Adjuvant chemotherapy (ACT) with 5-FU alone or 5-FU plus platinum after curative surgery improves the prognosis of pStage II-III gastric cancer (GC). However, only a subset of patients benefits from adjuvant platinum.
Zhiyuan Fan   +10 more
doaj   +1 more source

Platelet Reactivity and Response to Aspirin and Clopidogrel in Patients with Platelet Count Disorders

open access: yesCardiology Research and Practice, 2021
Background. Platelet reactivity and response to antiplatelet drugs, acetylsalicylic acid (ASA) and clopidogrel, in patients with thrombocytopenia and thrombocythemia can have a potentially important effect on the outcome.
Wiktor Kuliczkowski   +11 more
doaj   +1 more source

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