Results 51 to 60 of about 1,822,518 (269)

Low-grade appendiceal mucinous neoplasm (LAMN) as a mimicker of perforated diverticulitis: a case report [PDF]

, 2022
Christopher Shean, Janaka Balasooriya, James Fergusson   +2 more
openalex   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

P608: THE EXPRESSION OF CYTOR LNCRNA HAS POOR PROGNOSTIC VALUE IN CLL PATIENTS AND IS ASSOCIATED WITH MICROENVIRONMENTAL STIMULI.

HemaSphere, 2023
Lluís Hernández, Ferran Nadeu, Julio Delgado, Martí Duran-Ferrer, Dario Rafael Romero, Ruth Orellana Fernández, Tamara Bittolo, Riccardo Bomben, Valter Gattei, Elias Campo   +9 more
doaj   +1 more source

772 MHC-I skewing in mutant calreticulin-positive myeloproliferative neoplasms is countered by heteroclitic peptide cancer vaccination [PDF]

, 2021
Mathieu Gigoux, Roberta Zappasodi, Joseph Park, Cansu Cimen Bozkus, Levi Mangarin, David Redmond, Svena Verma, Sara Schad, Mariam M. George, Divya Venkatesh, Arnab Ghosh, Zaki Molvi, Baransel Kamaz, Anna E. Marneth, William S. Duke, Matthew Leventhal, Max Jan, Vincent T. Ho, Gabriela Hobbs, Trine Alma Knudsen, Vibe Skov, Lasse Kjær, Thomas Stauffer Larsen, Dennis Lund Hansen, R. Coleman Lindsley, Hans Carl Hasselbalch, Jacob Handlos Grauslund, Mads Hald Andersen, Morten Orebo Holmström, Timothy A. Chan, Raajit K. Rampal, Omar Abdel‐Wahab, Nina Bhardwaj, Ann Mullally, Jedd D. Wolchok, Taha Merghoub   +35 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Lymphadenectomy and Sentinel Lymph Node Biopsy in Patients with Endometrial Cancer in Intermediate and High-Intermediate Risk Groups: The Ukrainian Experience

International Journal of Women's Health
Olha Khoptiana,1 Valentyn Svintsitskyi,1 Sergiy Nespryadko,1 Natalia P Tsip,1 Teimuraz Gogisvanidze,2 Mikheil Dzimistarishvili,2 Dmytro Krasylenko,2 Mykhailo Serhiiovych Chetverikov,3 Igor Pavlovych Nigutsa,3,4 Dmytro Sumtsov,4 Pavlo Dolyk5 1Scientific ...
Khoptiana O, Svintsitskyi V, Nespryadko S, Tsip NP, Gogisvanidze T, Dzimistarishvili M, Krasylenko D, Chetverikov MS, Nigutsa IP, Sumtsov D, Dolyk P   +10 more
doaj  

Characterization of alternative splicing events and prognostic signatures in gastric cancer

Cancer Cell International
Background Accumulating evidences indicate that the specific alternative splicing (AS) events are linked to the occurrence and prognosis of gastric cancer (GC). Nevertheless, the impact of AS is still unclear and needed to further elucidation.
Nan Zhu, Yupeng Zhao, Wenjing Yan, Lan Wei, Qingqing Sang, Jianfang Li, Bingya Liu, Beiqin Yu   +7 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Malignant Alveolar Neoplasm in a 10-Month-Old French Bulldog

, 2022
Manoel Luiz Ferreira, Plínio de Araújo Oliveira Neto, Raul Rousso Filho, Bruna Guedes De Carvalho, PAULO CESAR SILVA, Valéria Duarte Reis Da Costa, Marcus Vinícius Alves da Silva, Fernando Alzamora Filho   +7 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source