Results 51 to 60 of about 1,230,212 (337)

Hierarchical Phenotyping and Graph Modeling of Spatial Architecture in Lymphoid Neoplasms [PDF]

arXiv, 2021
The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the first to hybridize local and global graph methods to profile orchestration and interaction of cellular components.
arxiv  

Automatic Detection of Blue-White Veil and Related Structures in Dermoscopy Images [PDF]

Computerized Medical Imaging and Graphics 32 (2008) 670-677, 2010
Dermoscopy is a non-invasive skin imaging technique, which permits visualization of features of pigmented melanocytic neoplasms that are not discernable by examination with the naked eye. One of the most important features for the diagnosis of melanoma in dermoscopy images is the blue-white veil (irregular, structureless areas of confluent blue ...
arxiv   +1 more source

The substrate of the biopsychosocial influences in the carcinogenesis of the digestive tract [PDF]

, 2016
Digestive cancer represents a severe public health problem, being one of the main causes of death. It is considered a multifactorial disease, with hereditary predisposition, environmental factors, and other factors involved in carcinogenesis.
Caragea, Daniel, Florescu, Cristina, Pirici, Daniel, Târtea, Elena A, Târtea, Georgică C, Vere, Cristin C   +5 more
core   +2 more sources

Liver Resection for Primary Hepatic Neoplasms. [PDF]

, 1988
Subtotal hepatic resection was performed in 356 patients; 87 had primary hepatic malignancies, 108 had metastatic tumors, and 161 had benign lesions including 8 traumatic injuries. The global mortality was 4.2%.
C. Couinaud, J. L. Lortat-Jacob, J. R. Craig, L. Abel, M. M. Berman, N. A. Goldsmith, O. H. Wangensteen, R. W. Raven, S. Iwatsuki, T. E. Starzl, T. E. Starzl, T. E. Starzl, T. E. Starzl, T. E. Starzl, Th. E. Starzl, W. Wendel, Y. G. Adam   +16 more
core   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Studying the emergence of invasiveness in tumours using game theory [PDF]

, 2008
Tumour cells have to acquire a number of capabilities if a neoplasm is to become a cancer. One of these key capabilities is increased motility which is needed for invasion of other tissues and metastasis. This paper presents a qualitative mathematical model based on game theory and computer simulations using cellular automata.
arxiv   +1 more source

Right trisegmentectomy for hepatic neoplasms [PDF]

, 1980
Thirty patients had right trisegmentectomy for 19 primary hepatic malignant tumors, 7 localized liver metastases and four benign lesions. A technical refinement that aided resection of bulky posterior and superior tumors was intrahepatic identification ...
Aldrete, JA, Koep, LJ, Lilly, JR, Putnam, CW, Starzl, TE, Weil, R   +5 more
core  

Comparison of the diagnostic accuracy of three current guidelines for the evaluation of asymptomatic pancreatic cystic neoplasms. [PDF]

, 2017
Asymptomatic pancreatic cysts are a common clinical problem but only a minority of these cases progress to cancer. Our aim was to compare the accuracy to detect malignancy of the 2015 American Gastroenterological Association (AGA), the 2012 International
Aslanian, Harry, Brooks, Christian A., Chabot, John A., Do, Catherine, Farrell, James J., Genkinger, Jeanine M, Gonda, Tamas A., Gress, Frank G., Kluger, Michael D., Kowalski, Thomas E., Loren, David E., Poneros, John M., Salem, Ronald R., Schrope, Beth, Sethi, Amrita, Siddiqui, Ali A., Xu, Ming-Ming, Yin, Shi   +17 more
core   +2 more sources

Palmitate acid promotes gastric cancer metastasis via FABP5/SP1/UCA1 pathway

Cancer Cell International, 2019
Background Gastric cancer (GC) has a clear predilection for metastasis toward omentum which is primarily composed of adipose tissue, combine with our previous research that long non-coding RNA Urothelial cancer associated 1 (UCA1) could promote the ...
Jiaomeng Pan, Qingqiang Dai, Tianqi Zhang, Chen Li   +3 more
doaj   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source