Results 21 to 30 of about 533,074 (342)

Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. [PDF]

PLoS ONE, 2013
Chronic inflammation in the stomach induces metaplasia, the pre-cancerous lesion that precedes inflammation-driven neoplastic transformation. While Hedgehog signaling contributes to the initiation of some cancers, its role in gastric transformation ...
Mohamad El-Zaatari, John Y Kao, Art Tessier, Longchuan Bai, Michael M Hayes, Clinton Fontaine, Kathryn A Eaton, Juanita L Merchant   +7 more
doaj   +1 more source

An aggressive verrucous carcinoma of the palate with rare presentations and recurrence: A case report and literature review [PDF]

Journal of Oral Health and Oral Epidemiology, 2020
BACKGROUND AND AIM: Oral verrucous carcinoma (OVC) is a rare malignant tumor with a complex etiology. This tumor is more prevalent in men and buccal mucosa is the most common site of OVC.
Sahar Mafi, Nader Navabi, Mahsa Kalantari   +2 more
doaj   +1 more source

Iron oxide nanoparticle-induced neoplastic-like cell transformation in vitro is reduced with protective amorphous silica coating.

Chemical Research in Toxicology, 2019
Iron oxide nanoparticles (IONP) have recently surged in production and use in a wide variety of biomedical and environmental applications. However, their potential long term health effects, including carcinogenesis, are unknown. Limited research suggests
Tiffany G. Kornberg, Todd A Stueckle, J. Coyle, R. Derk, P. Demokritou, Y. Rojanasakul, L. Rojanasakul   +6 more
semanticscholar   +1 more source

The role of E-cadherin in neoplastic evolution of epithelial cells

Успехи молекулярной онкологии, 2015
Interaction of the extracellular domains of the transmembrane proteins cadherins provides cell-cell adhesion. For many years epithelial E- cadherin was regarded as a tumor suppressor and was used as a prognostic marker in cancer.
N. A. Gloushankova, I. Yu. Zhitnyak, D. V. Ayollo, S. N. Rubtsova   +3 more
doaj   +1 more source

Squamous cell carcinoma arising in ovarian mature cystic teratoma: report of three cases

Journal of Pathology of Nepal, 2012
Malignant transformation of mature cystic teratoma of the ovary is rare. A wide variety of malignant tumors may arise within benign mature cystic teratoma.
R Bashyal, MC Lee
doaj   +1 more source

In Vitro Anticancer and Cancer-Preventive Activity of New Triterpene Glycosides from the Far Eastern Starfish Solaster pacificus

Marine Drugs, 2022
Sea stars or starfish (class Asteroidea) and holothurians or sea cucumbers (class Holothuroidea), belonging to the phylum Echinodermata (echinoderms), are characterized by different sets of glycosidic metabolites: the steroid type in starfish and the ...
Timofey V. Malyarenko, Olesya S. Malyarenko, Alla A. Kicha, Anatoly I. Kalinovsky, Pavel S. Dmitrenok, Natalia V. Ivanchina   +5 more
doaj   +1 more source

Hacking cell differentiation: transcriptional rerouting in reprogramming, lineage infidelity and metaplasia

EMBO Molecular Medicine, 2013
Initiating neoplastic cell transformation events are of paramount importance for the comprehension of regeneration and vanguard oncogenic processes but are difficult to characterize and frequently clinically overlooked.
Gonçalo Regalo, Achim Leutz
doaj   +1 more source

Malignant transformation of abdominal wall endometriosis to clear cell carcinoma: case report

São Paulo Medical Journal, 2017
BACKGROUND: Malignant transformation of endometriosis in the abdominal wall is a rare and still poorly understood event. Less than 30 cases have been reported in the worldwide literature. Most cases of solid tumors are report in a previous abdominal scar
João Kleber de Almeida Gentile, Renato Migliore, Fábio Jorge Neubaner Kistenmacker, Marcio Menezes de Oliveira, Rodrigo Biscuola Garcia, Fang Chia Bin, Pedro Marcos Santinho Bueno de Souza, José César Assef   +7 more
doaj   +1 more source

Dual cytoplasmic and nuclear localization of HTLV-1-encoded HBZ protein is a unique feature of adult T-cell leukemia

Haematologica, 2021
Adult T-cell leukemia-lymphoma (ATL), is a highly malignant T-cell neoplasm caused by human T-cell leukemia virus type 1 (HTLV-1), characterized by a poor prognosis.
Greta Forlani, Mariam Shallak, Alessandra Tedeschi, Ilaria Cavallari, Ambroise Marçais, Olivier Hermine, Roberto S. Accolla   +6 more
doaj   +1 more source

Equol, a Metabolite of the Soybean Isoflavone Daidzein, Inhibits Neoplastic Cell Transformation by Targeting the MEK/ERK/p90RSK/Activator Protein-1 Pathway*

Journal of Biological Chemistry, 2007
Daidzein and genistein are isoflavones found in soybean. Genistein is known to exhibit anticarcinogenic activities and inhibit tyrosine kinase activity.
N. Kang, K. Lee, E. A. Rogozin, Yong-Yeon Cho, Y. Heo, A. Bode, H. Lee, Z. Dong   +7 more
semanticscholar   +1 more source