Results 31 to 40 of about 533,074 (342)

Primary splenic lymphoma on top of intrahepatic splenosis: A unique case report

open access: yesRadiology Case Reports, 2022
Solid organ splenosis is a challenging diagnosis with many atypical imaging features that can overlap with neoplastic masses of the affected organ. We present a sporadic case of intrahepatic splenosis in a 68-year-old woman with transformation into a low-
Moataz Soliman, MD   +4 more
doaj   +1 more source

Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation. [PDF]

open access: yesPLoS ONE, 2011
High risk human papillomaviruses are squamous epitheliotropic viruses that may cause cervical and other cancers. HPV replication depends on squamous epithelial differentiation.
Svetlana Vinokurova   +1 more
doaj   +1 more source

Speeding through cell cycle roadblocks: Nuclear cyclin D1-dependent kinase and neoplastic transformation

open access: yesCell Division, 2008
Mitogenic induction of cyclin D1, the allosteric regulator of CDK4/6, is a key regulatory event contributing to G1 phase progression. Following the G1/S transition, cyclin D1 activation is antagonized by GSK3β-dependent threonine-286 (Thr-286 ...
Diehl J Alan, Pontano Laura L
doaj   +1 more source

Metabolic Plasticity of Tumor Cell Mitochondria

open access: yesFrontiers in Oncology, 2018
Mitochondria are dynamic organelles that exchange a multiplicity of signals with other cell compartments, in order to finely adjust key biological routines to the fluctuating metabolic needs of the cell.
Giuseppe Cannino   +4 more
doaj   +1 more source

Chromoblastomycosis evolving to sarcomatoid squamous cell carcinoma: A case report

open access: yesDermatology Reports, 2021
Chromoblastomycosis (CMB) is a cutaneous fungal infection caused by dematiaceous fungi. According to the World Health Organization CMB has been elected as a tropical disease, and it is prevalent in tropical and subtropical regions.
Walter Belda Jr.   +3 more
doaj   +1 more source

Hepatocellular carcinoma arising in a telangiectatic hepatocellular adenoma

open access: yesAnnals of Hepatology, 2013
Telangiectatic hepatocellular adenoma is a rare, recently recognized subtype of benign liver tumor that may very rarely undergo transformation into hepatocellular carcinoma.
María Fernanda González-Lara   +4 more
doaj   +1 more source

NF-κB signaling in neoplastic transition from epithelial to mesenchymal phenotype

open access: yesCell Communication and Signaling, 2023
NF-κB transcription factors are critical regulators of innate and adaptive immunity and major mediators of inflammatory signaling. The NF-κB signaling is dysregulated in a significant number of cancers and drives malignant transformation through ...
Amy Oh   +7 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

LRIG1 as a potential novel marker for neoplastic transformation in ocular surface squamous neoplasia.

open access: yesPLoS ONE, 2014
The leucine rich repeats and immunoglobulin-like protein 1 (LRIG1) is a newly discovered negative regulator of epidermal growth factor receptor (EGFR) and a proposed tumor suppressor.
Maho Nagata   +5 more
doaj   +1 more source

Spectrum of Sinonasal Lesions with Expression of p16 and Ki-67 in Premalignant Lesions and Squamous Cell Carcinomas [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Sinonasal masses are heterogeneous group of non-neoplastic and neoplastic lesions originating from epithelial, mesenchymal, haematolymphoid and neuroendocrine cells.
Madhumita Paul   +3 more
doaj   +1 more source

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