Low Rates of Digital Rectal Exam in an Academic Health System Represent a Missed Opportunity
ABSTRACT Background and Objectives Digital rectal exam (DRE) is an important screening tool for early cancer identification. DRE has become less routinely performed following removal from cancer screening guidelines. The effect of this decreased utilization has not been studied; this study sought to evaluate current DRE utilization and changes over ...
Kelly R. Bates+6 more
wiley +1 more source
Diffusion and Binding of Mismatch Repair Protein, MSH2, in Breast Cancer Cells at Different Stages of Neoplastic Transformation. [PDF]
Sigley J+7 more
europepmc +1 more source
LDOC1 silenced by cigarette exposure and involved in oral neoplastic transformation. [PDF]
Lee CH+8 more
europepmc +1 more source
Modulation of RASD2 by miRNA‐485‐5p Drives Thyroid Cancer Progression and Metastasis
ABSTRACT This study investigates the role of RASD2 (Ras Homolog Enriched In Striatum) in thyroid carcinoma progression and its modulation by microRNA‐485‐5p. Differential RASD2 expression patterns were initially identified through bioinformatic analysis of public databases.
Xiao‐Yu Li+7 more
wiley +1 more source
Cytological Alterations of Benign Thyroid Nodules Following Radiofrequency Ablation
This prospective study of 312 patients with benign thyroid nodules treated with radiofrequency ablation showed a 3.84% progression to Bethesda III cytology, all confirmed benign by molecular testing, with an 88% volume reduction at 60 months and no major complications.
Emad Kandil+6 more
wiley +1 more source
Malignant Transformation Rate of Oral Premalignant Disorders: A Large Database Analysis
ABSTRACT Objectives Oral leukoplakia (OL), oral lichen planus (OLP), and oral submucous fibrosis (OSF) are precancerous lesions known to progress to oral squamous cell carcinoma (OSCC). The transformation rates to OSCC are controversial and have been based on small, heterogeneous, single‐institution studies. We present the largest study to date looking
Andrew Meci+2 more
wiley +1 more source
Temporal‐Parotid Resection for Malignant Parotid Tumors: A Systematic Review
Parotid gland tumors represent a complex surgical challenge. Temporal‐parotid resection (TPR) is indicated to manage temporal bone invasion. Thirteen studies investigated the role of TPR in literature, including 336 patients. High rates of negative margins and local disease control are achieved with TPR.
Antonio Daloiso+7 more
wiley +1 more source
Evaluating Proton Versus Photon Therapy: A Call for Nuanced Decision‐Making
Journal of Medical Radiation Sciences, EarlyView.
Peter Gorayski, Hien Le, Frank Saran
wiley +1 more source
Expert Consensus on the Diagnosis and Treatment of Malignant Pericardial Mesothelioma
ABSTRACT Primary malignant pericardial mesothelioma (PMPM), a rare pericardium‐derived malignancy, urgently requires standardized diagnostic and therapeutic protocols. This consensus, established by the Chinese Alliance of Research for Mesothelioma (ChARM) through the integration of evidence‐based research and multicenter clinical expertise, addresses ...
Qing Ji+112 more
wiley +1 more source