Results 271 to 280 of about 22,017 (305)
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VASA. Zeitschrift fur Gefasskrankheiten, 2020
This review provides an updated overview of the emerging roles of neopterin derivatives in atherosclerosis. Neopterin, a metabolite of guanosine triphosphate, is produced by interferon-γ-activated macrophages and is expressed at high levels in ...
Takuya Watanabe
semanticscholar +1 more source
This review provides an updated overview of the emerging roles of neopterin derivatives in atherosclerosis. Neopterin, a metabolite of guanosine triphosphate, is produced by interferon-γ-activated macrophages and is expressed at high levels in ...
Takuya Watanabe
semanticscholar +1 more source
Neopterin in clinical practice
Clinica Chimica Acta, 1991Neopterin and the closely related biopterin belong to a group of pteridine compounds containing a 2-amino, 4-0~0, pyrimidino-pyrazino-(pterin) ring, with a 3-carbon side-chain on carbon 6. Pteridines were first described as pigments of insects and lower vertebrates [ll. During the past ten years increased concentrations of neopterin in body fluids have
M M, Müller +3 more
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Diseases of the Colon & Rectum, 1987
Neopterin is compared with other tumor markers in colorectal carcinoma. Its sensitivity is clearly lower than that of CEA, TPA and CA 19/9 and is even lower than the sensitivity of the erythrocyte sedimentation rate. The ability of neopterin to discriminate between different tumor stages is also lower than that of the other markers.
H, Putzki +3 more
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Neopterin is compared with other tumor markers in colorectal carcinoma. Its sensitivity is clearly lower than that of CEA, TPA and CA 19/9 and is even lower than the sensitivity of the erythrocyte sedimentation rate. The ability of neopterin to discriminate between different tumor stages is also lower than that of the other markers.
H, Putzki +3 more
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Experimental Dermatology, 1999
Abstract: Neopterin was discovered in bee larvae, in worker bees and in royal jelly. The compound was termed “neopterin” to denote that it might start a new (Greek, neo) epoch in pteridine research. Increased concentrations of neopterin were reported in patients with viral infections, suggesting that increased neopterin may originate from the immune ...
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Abstract: Neopterin was discovered in bee larvae, in worker bees and in royal jelly. The compound was termed “neopterin” to denote that it might start a new (Greek, neo) epoch in pteridine research. Increased concentrations of neopterin were reported in patients with viral infections, suggesting that increased neopterin may originate from the immune ...
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Determination of Neopterin as a Prognostic Indicator Using Neopterin-Imprinted Cryogel Membranes
2021Neopterin (Neo) is thought of as a key biomarker for the diagnosis and prognosis of a wide variety of diseases associated with cellular immune response. Therefore, it has become a vital need to be able to specifically determine the Neo concentration in human serum. Molecularly imprinted cryogels have come into prominence among other affinity systems by
Okan, Zenger +4 more
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Serum Neopterin After Lung Transplantation
Chest, 1993Neopterin (N), a marker for activated cell-mediated immunity, was assayed in the sera of 44 lung recipients early and late after transplantation. The study was a prospective, blind clinical trial designed to evaluate the following: (1) the daily dynamics of the serum neopterin/creatinine (N/C) ratio during the first 3 weeks after transplantation; (2 ...
M, Humbert +5 more
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Interleukin-2- and neopterin-induced neopterin release from peripheral blood mononuclear cells
Scandinavian Journal of Clinical and Laboratory Investigation, 1990Stimulation of peripheral blood mononuclear cells (PBMC) by the mitogenic lectins, phytohaemagglutinin (PHA) and concanavalin A (conA), the lymphokine gamma-interferon (gamma-IFN) and interleukin-2 (IL-2) and the pterin neopterin, caused an increased release of neopterin from those cells, with peak levels after 7 days of stimulation.
M, Barak, D, Merzbach, N, Gruener
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Molecular Immunology, 2005
Neopterin is well established as a reliable marker in HIV-1 infection. Neopterin concentrations measured in urine or serum indicate sensitively the course and progression of the disease as well as efficacy of anti-retroviral therapy. The main trigger for neopterin production is Th1-type cytokine interferon-gamma.
Barbara, Wirleitner +3 more
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Neopterin is well established as a reliable marker in HIV-1 infection. Neopterin concentrations measured in urine or serum indicate sensitively the course and progression of the disease as well as efficacy of anti-retroviral therapy. The main trigger for neopterin production is Th1-type cytokine interferon-gamma.
Barbara, Wirleitner +3 more
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Neopterin in Subacute Sclerosing Panencephalitis
1993Subacute sclerosing panencephalitis (SSPE) has a very poor prognosis. In recent years, the introduction of various treatments including inosiplex and interferon has somewhat improved the survival rate1,2. However, there are large variations in the response of patients.
H, Shintaku +6 more
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