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Early Reversal of Rapacuronium with Neostigmine
Anesthesiology, 1999Background Rapacuronium is a rapid-onset, short-acting neuromuscular relaxant. This multiple-center study determined neuromuscular recovery when neostigmine was given 2 or 5 min after rapacuronium. Methods One hundred seventeen patients were randomized to receive two different doses
François Donati+3 more
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Journal of the American Medical Association, 1948
ABSTRACT To the Editor:— With great interest we noted the article of George Merrill in the May 22 issue of THE JOURNAL entitled "Neostigmine Toxicity: Report of Fatality Following Test for Myasthenia Gravis." To emphasize the advisability of awareness of the untoward reactions attendant on the use of neostigmine, we call attention to observations on ...
E. Adelson, F. Brunn
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ABSTRACT To the Editor:— With great interest we noted the article of George Merrill in the May 22 issue of THE JOURNAL entitled "Neostigmine Toxicity: Report of Fatality Following Test for Myasthenia Gravis." To emphasize the advisability of awareness of the untoward reactions attendant on the use of neostigmine, we call attention to observations on ...
E. Adelson, F. Brunn
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Degradation Kinetics of Neostigmine in Solution
Drug Development and Industrial Pharmacy, 2000The degradation kinetics of neostigmine were studied in aqueous solutions with varied pH from 1.5 to 9.9 under accelerated storage conditions. The stability of neostigmine in solutions containing propylene glycol or polyethylene glycol 400 was also investigated.
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