Results 171 to 180 of about 97,146 (264)

Higher plasma vitamin D levels are not causally associated with less age‐related macular degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Higher levels of plasma 25‐hydroxyvitamin D have been associated with a lower risk of age‐related macular degeneration (AMD). We investigated observational and potential causal associations of plasma 25‐hydroxyvitamin D with the risk of AMD in two large contemporary population‐based prospective studies and a genetic case–control ...
Sabina O. Beheshti   +3 more
wiley   +1 more source

Occurrence, progression and risk factors of macular atrophy in neovascular age‐related macular degeneration according to neovascularization subtypes

open access: yesActa Ophthalmologica, EarlyView.
Abstract Objective To assess the occurrence, risk factors, and progression of macular atrophy (MA) according to macular neovascularization (MNV) subtype in neovascular AMD (nAMD). Methods This multicentre retrospective observational cohort study included 416 eyes with nAMD, followed for at least 12 months and treated with anti‐VEGF.
Amandine Moulin   +11 more
wiley   +1 more source

CD93—An emerging vascular target in cancer therapy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira   +3 more
wiley   +1 more source

USP25 promotes ferroptosis in diabetic retinopathy by deubiquitinating p53 and suppressing the GPX4/SLC7A11 axis

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Objective To explore the expression of the deubiquitinase (DUB) USP25 in diabetic retinopathy (DR) and its mechanistic role in regulating ferroptosis. Methods Bioinformatics was used to screen for DR‐related DUB candidate genes. USP25 expression was validated in a streptozotocin‐induced diabetic mouse model and high glucose (HG)‐treated ARPE ...
Yanjun Gao   +3 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy